[摘要]雄激素性脱发(Androgenetic alopecia，AGA)作为最常见的脱发类型，表现为头发密度进行性减少，是一种依赖雄激素且遗传的多发性疾病，往往对患者的外貌和心理以及职业选择产生严重影响。因此，近年来国内外有关雄激素性脱发的发病机制及其治疗研究成为热点，该综述就AGA发病机制中氧化应激的相关性进行阐述，为AGA的精准治疗奠定科学依据。

    [关键词]雄激素性脱发；氧化应激；wnt/β-catenin信号通路；TGF-β信号通路

    [中国分类号]R758.71" " [文献标志码]A" " [文章编号]1008-6455(2025)02-0189-04

    The Pathogenesis and Research Progress of Oxidative Stress on Androgenic Alopecia

    MA Xiaomin1，2， LIANG Danni2，3， ZHANG Kaiyun2，3， ZHANG Jia2， ZHANG Guohui1，2

    ( 1.Baotou Clinical Medical College Inner Mongolia Medical University， Baotou 014040， Inner Mongolia， China; 2.Department of Dermatology， Baotou Central Hospital， Baotou 014040， Inner Mongolia， China; 3.Inner Mongolia University of Science and Technology Baotou Medical College， Baotou 014040， Inner Mongolia， China )

    Abstract： As the most common type of hair loss， androgenetic alopecia is characterized by progressive loss of hair density. It is an androgen-dependent and genetic multiple disease， which often has a serious impact on the patient's appearance and psychology， as well as career choices.Therefore， research on the pathogenesis and treatment of androgenetic alopecia at home and abroad has become a hot spot in recent years. This review will explain the correlation of oxidative stress in the pathogenesis of AGA ......