[摘要]目的：分析甲泼尼龙对肿块型肉芽肿性乳腺炎术后乳房美学与康复效果的改善作用。方法：根据治疗方案将2021年1月-2023年1月笔者科室收治的97例肿块型肉芽肿性乳腺炎患者分为对照组(n=49)和激素组(n=48)。对照组行乳腺病变组织扩大切除术治疗，激素组在乳腺病变组织扩大切除术的基础上给予甲泼尼龙治疗，两组均随访1年。比较两组术后疼痛情况、并发症、疗效、血清炎症指标、术后1年乳房美学效果及患者满意度。结果：激素组切口愈合时间、住院时间均短于对照组(P<0.05)；术后3个月，激素组总有效率高于对照组(P<0.05)；术后7、14 d激素组VAS评分低于对照组(P<0.05)；术后8周，激素组血清IL-6、CRP、IL-2水平低于对照组(P<0.05)；术后1年，激素组乳房美学效果优良率和患者满意度高于对照组(P<0.05)。结论：乳腺病变组织扩大切除术后应用甲泼尼龙可促进肿块型肉芽肿性乳腺炎患者术后康复、抑制炎症指标异常，进而有助于改善疗效及预后情况，巩固乳房美学效果，获得患者认可，安全性良好。

    [关键词]肿块型肉芽肿性乳腺炎；甲泼尼龙；康复；预后；美学效果

    [中图分类号]R622" " [文献标志码]A" " [文章编号]1008-6455(2025)06-0048-04

    Effect of Methylprednone on Breast Aesthetics and Rehabilitation after Mastitis with Lump-type Granulomatous Disease

    SUO Pengfeng， BAI Yanhua， ZHANG Yiying

    ( Department of Breast Surgery， Zhangjiakou First Hospital， Zhangjiakou 075000， Hebei， China )

    Abstract： Objective" To analyze the effect of methylprednone on breast aesthetics and rehabilitation after mastitis with lump-type granulomatous disease. Methods" 97 patients with mass granulomatous mastitis admitted to the author's hospital from January 2021 to January 2023 were divided into the non-hormone group (n=49) and the hormone therapy group (n=48) by the treatment plan. The non-hormone group was treated with enlarged resection of breast lesions ......