[摘要]脱发是如今困扰现代人的难题之一，当前主要治疗手段(药物治疗与手术干预)虽有效果，但仍存在一定局限性。细胞外囊泡(Extracellular vesicles，EV)携带蛋白质、RNA和microRNA等重要物质，可作为细胞外信使并促进细胞间的通讯，从而参与多种生理过程。最近的研究表明，细胞外囊泡可以促进毛发生长。基于此，本文总结了关于细胞外囊泡在不同毛发相关细胞中促进毛发生长的作用，以期为临床应用细胞外囊泡治疗脱发提供新的思路。

    [关键词]细胞外囊泡；外泌体；毛发生长；毛乳头细胞；毛基质细胞

    [中图分类号]R758.71" " [文献标志码]A" " [文章编号]1008-6455(2025)06-0187-04

    Research Progress on Extracellular Vesicles Promoting Hair Growth

    SONG Yuanming1， LI Yumei2

    ( 1.Department of Dermatology， Inner Mongolia Medical University Affiliated Hospital， Hohhot 010107， Inner Mongolia， China; 2.Department of Dermatology， Jiangsu University Affiliated Hospital， Zhenjiang 212001， Jiangsu， China )

    Abstract： Hair loss is a common problem that afflicts modern individuals. Currently， the primary methods for treating hair loss are medication and surgery， but these treatments still have some limitations. Extracellular vesicles (EV) contain proteins， RNA， and microRNAs that can be transported to recipient cells， functioning as extracellular messengers and participating in cell-to-cell communication. Recent research has demonstrated that extracellular vesicles can stimulate hair growth. This article summarizes the role of extracellular vesicles in promoting hair growth in various hair-related cells and offers new insights into the use of extracellular vesicles for treating hair loss. ......