[摘要]敏感性皮肤常表现为皮肤受到轻微外界刺激后产生不适感觉(如：刺痛、烧灼感、瘙痒、刺麻等)。目前，敏感性皮肤的患病率在女性中高达60%～70%，在男性中高达50%～60%。敏感性皮肤的病因及发病机制复杂多样，发病机制主要涉及皮肤屏障功能受损、皮肤感觉神经功能障碍、皮肤微生物群紊乱、血管反应性增高、转录组学等多方面，常由多种机制共同参与组成。敏感性皮肤可能是皮肤的状况或皮肤及皮肤外疾病的表现。本文就敏感性皮肤的流行病学、发病机制及相关疾病进行综述。

    [关键词]敏感性皮肤；病因；流行病学；发病机制；相关疾病

    [中图分类号]R758.22" " [文献标志码]A" " [文章编号]1008-6455(2025)06-0195-04

    Progress in Pathogenesis and Related Diseases of Sensitive Skin

    WANG Bingxia1， GUAN Mengmeng2， KANG Xiaojing2， SHEN Xiaofeng1

    ( 1.The Fifth Clinical College of Xinjiang Medical University， Urumqi 830011， Xinjiang， China; 2.Department of Dermatology and Venereology， People’s Hospital of Xinjiang Uygur Autonomous Region， Xinjiang Clinical Research Center for Dermatologic Diseases， Xinjiang Key Laboratory of Dermatology Research ( XJYS1707 ) ， Urumqi 830001， Xinjiang， China )

    Abstract： Sensitive skin often manifests as a feeling of discomfort (such as tingling， burning， itching， tingling， etc.) caused by a slight external stimulation of the skin. The prevalence of sensitive skin is currently as high as 60%-70% in women and as high as 50%-60% in men. The etiology and pathogenesis of sensitive skin are complex and diverse ......