脂肪来源干细胞移植在创面修复治疗中的应用研究进展
[摘要]创面修复是现阶段研究的热点,在修复过程中处理不当极易造成创面愈合不良继而形成慢性创面,对患者生活健康造成影响。脂肪来源干细胞(Adipose-derived stem cells,ADSCs)以来源充足、易获取以及体外增殖能力强等优势,在促进组织修复及再生领域具有较好的应用前景。本文就ADSCs的来源、功能及其在创面修复治疗中的作用机制等展开综述,为创面修复治疗提供参考意义。[关键词]脂肪来源干细胞(ADSCs);创面修复;愈合与再生;作用机制
[中图分类号]R641" " [文献标志码]A" " [文章编号]1008-6455(2025)07-0186-04
Research Progress on the Application of Adipose-derived Stem Cells Transplantation in Wound Repair
WANG Feng, LU Xuelan, LI Linling, DIAO Jielin, ZHONG Fangyu, HE Jiale, CHEN Lang
( Department of Plastic and Aesthetic Burns, Affiliated Hospital of Sichuan North Medical College, Nanchong 637000,
Sichuan, China )
Abstract: Wound repair is a hot spot of current research. Improper treatment during repair can easily lead to poor wound healing and then chronic wounds, affecting the patients’ life and health. Adipose-derived stem cells (ADSCs) have good application prospects in promoting tissue repair and regeneration due to their advantages of sufficient source, easy access and strong proliferation ability in vitro. Herein, the source, function and mechanism of ADSCs in wound repair were reviewed to provide reference for wound repair. ......
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