[摘要]目的：探讨超脉冲点阵CO2激光联合强脉冲光治疗面部痤疮凹陷性瘢痕的疗效。方法：选取2021年10月-2023年5月笔者医院收治的92例面部痤疮凹陷性瘢痕患者，按照随机数字表法分为单一治疗组和联合治疗组，每组46例。单一治疗组患者接受超脉冲点阵CO2激光治疗，联合治疗组患者接受超脉冲点阵CO2激光和强脉冲光联合治疗，评估两组患者临床有效率，温哥华瘢痕评估量表(Vancouver scar assessment scale，VSS)评估瘢痕严重程度，比较皮肤生理指标，调查患者满意度，统计不良反应发生率。结果：联合治疗组临床有效率高于单一治疗组(P<0.05)；治疗后两组VSS评分、经皮水分丢失量均低于治疗前，角质层水分含量均高于治疗前(P<0.05)；治疗后，联合治疗组患者VSS评分、经皮水分丢失量均低于单一治疗组，角质层水分含水量高于单一治疗组(P<0.05)；联合治疗组患者满意度高于单一治疗组，不良反应发生率低于单一治疗组(P<0.05)。结论：超脉冲点阵CO2激光联合强脉冲光对面部痤疮凹陷性瘢痕患者具有良好的临床疗效，可提高患者满意度，减少不良反应。

    [关键词]超脉冲点阵CO2激光；强脉冲光；痤疮；凹陷性瘢痕；联合治疗

    [中图分类号]R758" " [文献标志码]A" " [文章编号]1008-6455(2025)09-01000-04

    Analysis of Curative Effect of Ultra-pulsed Fractional CO2 Laser Combined with Intense Pulsed Light in the Treatment of Depressed Scar of Facial Acne

    ZHU Wenting， JIANG Ninglan， XU Wenjing， BAO Qiuyu

    ( Department of Dermatology， First Affiliated Hospital of Hunan University of Traditional Chinese Medicine， Changsha 410007， Hunan， China )

    Abstract： Objective" To investigate the curative effect of" ultra-pulsed fractional CO2 laser combined with intense pulsed light in the treatment of depressed facial acne scar. Methods" Ninety-two patients with depressed facial acne scar admitted to the author's hospital from October 2021 to May 2023 were divided into single treatment group and combined treatment group according to random number table method ......