[摘要]目的：探究丹参酮胶囊联合粉刺去除术及红蓝光治疗对中重度痤疮的治疗效果。方法：纳入2021年8月-2023年8月笔者医院收治的120例中重度痤疮，随机分为对照组(n=60，给予常规治疗)，观察组(n=60，给予丹参酮胶囊联合粉刺去除术及红蓝光治疗)，比较两组治疗后临床疗效，比较两组治疗前和治疗4周后皮损体征、炎症因子水平[白介素-8(IL-8)、肿瘤坏死因子-ɑ(TNF-ɑ)、C-反应蛋白(CRP)]，比较不良反应总发生率，比较两组治疗后半年、1年复发率。结果：观察组总有效率(86.67%)高于对照组(71.66%)(χ2=4.093，P<0.05)；治疗后，与对照组相比，观察组皮损体征各项评分更低(t=6.567、8.622、9.088，P<0.05)；治疗后，与对照组相比，观察组CRP、TNF-ɑ、IL-8水平更低(t=6.300、7.198、4.594，P<0.05)；两组不良反应总发生率比较，差异无统计学意义(P>0.05)；观察组治疗后半年(5%)、治疗后1年(8.33%)复发率低于对照组(16.67%、23.33%)(χ2=4.227、5.065，P<0.05)。结论：丹参酮胶囊联合粉刺去除术及红蓝光治疗中重度痤疮，能够明显提高临床疗效，改善皮损体征，减轻炎症反应，降低复发率，安全有效，值得临床推广。

    [关键词]丹参酮胶囊；粉刺去除术；红蓝光治疗；中重度痤疮；复发率

    [中图分类号]R758.73+3" " [文献标志码]A" " [文章编号]1008-6455(2025)09-0108-04

    Efficacy of Tanshinone Capsule Combined with Acne Removal and Red and Blue Light Therapy on Recurrence Rate of Moderate-to-severe Acne

    CHEN Gangxing1， XIA Yushan2

    ( 1. Department of Pharmacy， 2. Department of Traditional Chinese Medicine and Dermatology， Weiyuan County People's Hospital， Neijiang 642450， Sichuan， China )

    Abstract： Objective" To explore the therapeutic effect of Tanshinone Capsule combined with acne removal and red and blue light therapy on moderate-to-severe acne. Methods" Totally 120 patients with moderate-to-severe acne in the hospital were included from August 2021 to August 2023 ......