[摘要]目的：分析富血小板纤维蛋白(Platelet-rich plasma，PRF)牙髓血运重建术对年轻恒牙牙髓坏死伴根尖病变患者牙髓活力和根面美观度的影响。方法：选取2020年8月-2022年8月山西省中西医结合医院收治的80例(共80颗患牙)年轻恒牙牙髓坏死伴根尖病变患者为研究对象。根据数字表法随机将患者分为PRF组和对照组，每组40例(各40颗患牙)，对照组采用常规牙髓血运重建术进行治疗，PRF组采用PRF牙髓血运重建术治疗。比较两组患者治疗后3个月的临床疗效、牙髓活力以及治疗后3个月内的并发症发生情况。比较两组患者治疗前和治疗后3个月的牙根长度、根管壁厚度和美观度评分。结果：PRF组总有效率95.00%，高于对照组的80.00%(P<0.05)。温度检测法显示，PRF组治疗后牙髓活力整体优于对照组(P<0.05)。治疗后，两组患者牙根长度、根管壁厚度和美观度评分均明显改善，且PRF组牙根长度长于对照组，根管壁厚度厚于对照组，美观度评分高于对照组(均P<0.05)。两组患者并发症总发生率比较，差异无统计学意义(P>0.05)。结论：PRF牙髓血运重建术治疗年轻恒牙牙髓坏死伴根尖病变患者疗效明确，能有效改善牙髓活力和根面美观度，促进牙根生长发育，且具有一定安全性。

    [关键词]牙髓血运重建术；恒牙牙髓坏死；根尖病变；富血小板纤维蛋白(PRF)；牙髓活力；根面美观度

    [中图分类号]R781.31" " [文献标志码]A" " [文章编号]1008-6455(2025)09-0167-04

    Observation on the Therapeutic Effect of PRF Pulp Revascularization in the Treatment of Pulp Necrosis with Apical Lesions in Young Permanent Teeth

    YING Xiaomin， ZHU Guohong， CUI Ting

    ( Department of Stomatology， Shanxi Hospital of Integrated Traditional and Western Medicine， Taiyuan 030013，

    Shanxi， China )

    Abstract： Objective" To analyze the effects of platelet-rich fibrin (PRF) pulp revascularization on pulp vitality and root aesthetics in patients with pulp necrosis of young permanent teeth and apical lesions. Methods" A total of 80 patients (80 offending teeth) with pulp necrosis of young permanent teeth and apical lesions in Shanxi Hospital of Integrated Traditional and Western Medicine were enrolled between August 2020 and August 2022. According to random number table method ......