[摘 要] 目的：探讨病毒灭活冰冻血浆与新鲜冰冻血浆中部分有效成分的质量变化。方法：采集50袋新鲜血浆，分成A、B两组，分别对其进行检测，内容包括PT，TT，APTT，Fg，TP、ALB及凝血因子FⅧ、FⅤ。结果：病毒灭活冰冻血浆中的总蛋白、凝血因子FⅧ、FⅤ和Fg等的含量均有一定程度的降低。但大都在30%以内，在可接受的范围内。结论：采用MB光化学法病毒灭活血浆不影响临床应用，其利大于弊。

    [关键词] 病毒灭活冰冻血浆；凝血因子；因子活性；血浆蛋白

    [Abstract] Objective: To explore virus inactivated frozen plasma and fresh frozen plasma part of effective ingredients of quality changes. Methods: To gather 50 bags fresh plasma, A and B is divided into two groups , detected PT，TT，APTT，Fg，TP,ALB,FⅧ,FⅤ respectively .Results :The content of TP, FⅧ, FⅤ and Fg in virus inactivated frozen plasma with a certain degree of reduced , but mostly within 30%, in the acceptable range .Conclusions :The MB virus inactivated plasma did not influence the clinical application, it did More good than harm .

    [Key Words] virus inactivated frozen plasma clotting factor factor activity plasma protein

    新鲜冰冻血浆内含有各种凝血因子及各种血浆蛋白 ......