益肾活血汤对糖尿病大鼠肾功能保护作用的实验研究(3)
中药益肾活血汤通过改善脂代谢紊乱、抗非酶糖化和氧化应激来改善肾功能，从而延缓糖尿病肾病的发生，但无降低血糖的作用，并且低剂量和高剂量之间并无太大的差别。
参考文献
[1] Vlassara H, Bucala R，Striker L.Pathogenic effects of advanced glycosylation;biochermical and clinical implications for diabetes and aging[J].Lab Invest,1994,70(1)：138-146.
[2] William IS.Lipotoxicity and glucitoxicity in type 2 diabetes[J].Postgraduate Medicine,2001,109:55-68.
[3] Mcgarry JD,Dpbbins RL.Fatty acids,Lipotoxicity and insulin secretion[J].Diabetologia,1999,42:128-141.
[4] 宋林萱，孔庆爱.中医药对糖尿病肾病的认识[J].中医药信息，2003，20(3)：3-4.
[5] 刘其刚.中西医结合治疗糖尿病肾病的临床研究[J].上海中医药杂志，2005，39(2)：29-30.
[6] 罗飞. 糖尿病肾病早期检测标志物研究新进展[J].国外医学•儿科学分册，2003，30(1)：7-10.
[7] Dominguec JH,Tang N,Xu W,et al.Studies of renal injury Ⅲ:lipid-induced nephropathy in type Ⅱ diabetes[J].kidney Int,2000,57:92-104.
[8] Ha H，Lee HB.Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose[J].Kidney Int,2000,77(suppl):S19-S25.
[9] Cohen MP,Ziyadeh FN.Role of Amadori-modified nonenzymatically glycated serum proteins in the pathogenesis of diabetic nephropathy[J].J Am Soc Nephrol,1996,7(2):183-189., 百拇医药(高国丽 车光升 董 瑶 苏 丹 刘志梅 崔培红 姜 源 王 )
参考文献
[1] Vlassara H, Bucala R，Striker L.Pathogenic effects of advanced glycosylation;biochermical and clinical implications for diabetes and aging[J].Lab Invest,1994,70(1)：138-146.
[2] William IS.Lipotoxicity and glucitoxicity in type 2 diabetes[J].Postgraduate Medicine,2001,109:55-68.
[3] Mcgarry JD,Dpbbins RL.Fatty acids,Lipotoxicity and insulin secretion[J].Diabetologia,1999,42:128-141.
[4] 宋林萱，孔庆爱.中医药对糖尿病肾病的认识[J].中医药信息，2003，20(3)：3-4.
[5] 刘其刚.中西医结合治疗糖尿病肾病的临床研究[J].上海中医药杂志，2005，39(2)：29-30.
[6] 罗飞. 糖尿病肾病早期检测标志物研究新进展[J].国外医学•儿科学分册，2003，30(1)：7-10.
[7] Dominguec JH,Tang N,Xu W,et al.Studies of renal injury Ⅲ:lipid-induced nephropathy in type Ⅱ diabetes[J].kidney Int,2000,57:92-104.
[8] Ha H，Lee HB.Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose[J].Kidney Int,2000,77(suppl):S19-S25.
[9] Cohen MP,Ziyadeh FN.Role of Amadori-modified nonenzymatically glycated serum proteins in the pathogenesis of diabetic nephropathy[J].J Am Soc Nephrol,1996,7(2):183-189., 百拇医药(高国丽 车光升 董 瑶 苏 丹 刘志梅 崔培红 姜 源 王 )