清补活血法对白塞氏综合征患者负性情绪及生活质量的干预(1)
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摘 要:目的:研究白塞氏综合征(BD)患者治疗前后负性情绪和生活质量的变化及清补活血法的干预作用,进一步评价清补活血法对BD的临床疗效。方法:将符合入选标准的108例BD患者,随机分为清补活血汤组(治疗组)54例,泼尼松组(对照组)54例。采用焦虑自评量表(SAS)、抑郁自评量表(SDS)、SF-36生存质量测定表进行问卷调查,采用半定量症状分级法对BD患者相关临床症状积分统计,进行前后对比治疗研究。结果:BD患者焦虑抑郁指数(SAS+SDS积分)较健康人明显升高(P<0.05);BD患者生活质量(生理功能、生理职能、躯体疼痛、总体健康、活力、社会功能、情感职能和精神健康)有不同程度的下降,与健康人比较有显著性差异(P<0.05或P<0.01);经治疗后两组患者上述各观察指标有不同的升落,与治疗前比较有显著性差异(P<0.05或P<0.01),治疗后治疗组与对照组比较,差异有显著性(P<0.05或P<0.01)。结论:BD患者处于轻中度精神抑郁状态,生活质量有一定程度的下降,清补活血法可改善BD患者的负性情绪,提高生活质量。
关键词:白塞氏综合征;焦虑抑郁指数;生活质量;负性情绪
中图分类号:R395.1
文献标识码:B
文章编号:1673-7717(2012)04-0810-03
Intervention of Clear Supplementing And Blood-Activating Method on
Negative Emotions And Life Quality of Behcet's Syndrome Patients
SHI Yan-zhang1,LI Gui2, JIA Feng-xin2, GAO Xiang-hong3, YUN Ya-qing4,WANG Yong-hui4
(1. Center Hospital in Qiuxian,Qiuxian 057450,Hebei,China;
2. Ping'an Hospital,Shijiazhuang 050021,Hebei,China;
3. Handan Hospital of Traditional Chinese Medicine,Handan 056000,Hebei,China;
4. Gaoyang Hospital of Traditional Chinese Medicine,Gaoyang 071500,Hebei,China)
Abstract:Objective: The changes of negative emotions and life quality of BD patients before and after treatment were compared and the intervention of clear supplementing and blood-activating method was studied so as to evaluate the effect. Methods: 108 cases met the criterion were involved and randomly divided into treatment group (54 cases) and control group (54 cases). SAS, SDS and SF-36 surviving testing table were used. Clinical symptoms scores comparison was made by semiquantitative symptom grading method. Results: The anxiety-depression index (SAS+SDS) of BD patients obviously increased than that of healthy people(P<0.05);quality life of BD patients had decreased in and compared with healthy people, there was significant differentce(P<0.05 or P<0.01). After treatment, the above indexes have different increase and decrease; and there was significant difference compared before treatment. The comparison before and after treatment had obvious differences(P<0.05 or P<0.01). Conclusion: BD patients are in moderate depression condition and the life quality has decreased to some extent. Clearing supplementing and blood-activating method can rectify the negative emotions and improve life quality ......
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