氨溴索对慢性阻塞性肺疾病患者氧化应激的影响
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【摘要】目的：研究氨溴索针剂对慢性阻塞性肺疾病(COPD)急性加重期患者氧化与抗氧化能力的影响。方法：COPD急性加重期患者，采用氨溴索针剂治疗，检测患者血清丙二醛(MDA)、超氧化物歧化酶活性(SOD)水平。并比较两组患者总有效率。结果：氨溴索治疗显著降低患者血清MDA含量，显著增加SOD水平，总有效率提高。结论：氨溴索能减轻COPD 急性加重期患者氧化应激程度，提高患者抗氧化能力，对 COPD患者有一定辅助治疗价值。
【关键词】氧化应激；氨溴索；慢性阻塞性肺疾病
文章编号：1009-5519(2008)05-0654-02 中图分类号：R5 文献标识码：A
Effect of ambroxol on oxidative stress in the patients with COPD
LIANG Xiong，MA Yu-xia
(Department of Respiratory Disease，Baoan People's Hospital of Shenzhen，GuangDong 518101，China)
【Abstract】Objective:To investigate the effect of ambroxol on oxidative stress in the patients with chronic obstructive pulmonary disease(COPD). Methods：Patients with COPD were treated with ambroxol. The levels of serum MDA and SOD were determined. Results：After the application of ambroxol ......
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