丹皮酚-β-环糊精包合物制备工艺研究
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【摘要】目的:优选丹皮酚-β-环糊精包合物的制备工艺。方法:采用正交试验的方法,以利用率和包封率为评价指标,筛选丹皮酚-β-环糊精包合物制备的最佳工艺条件。结果:最佳制备工艺为1份丹皮酚,24份40%酒精,8份β-环糊精,超声处理时间为40 min。结论:该工艺合理、稳定可行,对丹皮酚-β-环糊精包合物的制备效率较高。
【关键词】丹皮酚;正交试验;丹皮酚-β-包合物
文章编号:1009-5519(2008)07-0958-02 中图分类号:R28 文献标识码:A
Study on the preparation process of paeonol-β-cyclodextrin
YANG Zong-fa,ZHANG Rong-fa,JIANG Shang-fei,et al.
(Chongqing Pharmaceutical College,Chongqing 400030,China)
【Abstract】0bjective:To optimize the preparation process of paeonol-β-cyclodextrin.Methods:The optimum preparation process was selected with the orthogonal test.The optimal technological conditions were acquired by the evaluation of the availability and the encapsulation efficiencies.Results:The optimal preparation conditions of paeonol-β-cyclodextrin were as follows: the proportion of paeonol:alcohol:paeonol-β-cyclodextrin=1:24:8 ......
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