当前位置: 首页 > 期刊 > 《现代医药卫生》 > 2008年第15期
编号:11669956
GATA-4、NKx2-5转录因子的研究进展(3)

     [12] Kasahara H,Lee B,Schott JJ,et al.Less of function and inhibitory effects of human CSX/NKx215 homeop rotein mutations associated with congenital heart disease[J].J Clin Invest,2000,106: 299.

    [13] Kasahara H,Usheva A,Ueyama T,et al. Characterizationof homo and heterodimerization of cardiac Csx/ Nkx2.5 homeoprotein[J].J BiolChem,2001,276 (7):4 570280.

    [14] Bodmer R.The gene tinman is required for specification of the heartand visceral muscles in Drosophila[J]. Development,1993,118 (3):719229.

    [15] Lyons I,Parsons LM,Hartley L,et al.Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5[J].Genes Dev,1995,9 (13) : 1654266.

    [16] Scohtt JJ,Benson DW,Basson CT, et al.Congenital heart disease caused by nutations in the transcription factor NKX2-5[J].Science,1998,281(5 373) :108211.

    [17] Stennard FA,Costa MW, Elliott DA,et al.Cardiac Tbox factor Tbx20directly interacts with Nkx2-5,GATA-4,andGATA5 in regu lation of gene expression in the developing heart[J].Dev Biol,2003,262(2):206224.

    [18] Hirota Y,Sawamoto K,Okano H.tincar encodes a novel transmem-brane protein expressed in the Tinman-expressing cardioblasts of Drosophila[J].Gene Expr Patterns,2002,2(3~4):323.

    收稿日期:2008-01-16 修回日期:2008-03-31(冉 莉 文格波)
上一页1 2 3
    娣団剝浼呮禒鍛返閸欏倽鈧喛绱濇稉宥嗙€幋鎰崲娴f洑绠e楦款唴閵嗕焦甯归懡鎰灗閹稿洤绱╅妴鍌涙瀮缁旂姷澧楅弶鍐ㄧ潣娴滃骸甯拋妞剧稊閺夊啩姹夐敍宀冨閹劏顓绘稉鐑橆劃閺傚洣绗夌€规粏顫﹂弨璺虹秿娓氭稑銇囩€硅泛鍘ょ拹褰掓鐠囦紮绱濈拠鐑藉仏娴犺埖鍨ㄩ悽浣冪樈闁氨鐓¢幋鎴滄粦閿涘本鍨滄禒顒佹暪閸掍即鈧氨鐓¢崥搴礉娴兼氨鐝涢崡鍐茬殺閹劎娈戞担婊冩惂娴犲孩婀扮純鎴犵彲閸掔娀娅庨妴锟�

   瀵邦喕淇婇弬鍥╃彿  閸忚櫕鏁為惂鐐  鐠囧嫯顔戦崙鐘插綖  閹兼粎鍌ㄩ弴鏉戭樋