李承碧，唐春梅(荣昌区人民医院，重庆462460)

    ·论著·

    不同剂量孕酮针治疗先兆流产临床效果探讨

    李承碧，唐春梅△

    (荣昌区人民医院，重庆462460)

    目的探讨不同剂量孕酮(P)治疗先兆流产的临床效果。方法选取该院2012年1月至2014年12月收治的早孕先兆流产患者126例作为研究对象，采用随机数字表法分为A、B、C三组，每组42例，分别给予肌内注射P针每天20、40、60mg，比较三组患者治疗后血清P、血清β-人绒毛膜促性腺激素(β-HCG)水平，三组患者妊娠至足月例数、不良反应、稽留流产及完全流产发生率。结果A组：P(49.67±9.62)ng/mL、血清β-HCG(5 053.40±90.67)mU/mL；B组：P (50.23±8.24)ng/mL、血清β-HCG(5 052.30±88.43)mU/mL；C组：P(48.54±12.64)ng/mL、血清β-HCG(5 054.50±87.65)mU/mL；三组孕妇治疗后血清P及β-HCG水平比较，差异均无统计学意义(P>0.05)；三组患者妊娠至足月、不良反应及完全流产发生率比较，差异无统计学意义(P>0.05)；C组患者的稽留流产发生率均明显高于A、B组，差异均有统计学意义(P<0.05)。结论先兆流产患者经P安胎治疗后，妊娠结局与P剂量无明显关系，但大剂量P针会使稽留流产发生率增高。

    孕酮；流产，先兆；子宫收缩；绒毛膜促性腺激素；妊娠初期

    【Abstract】Objective To explore the effect of different doses of progesterone(P)in the treatment of threatened abortion. M ethods A total of 126 cases of early pregnancy threatened abortion in our hospital from January 2012 to December 2014 were selected and divided into the group A，B and C according to the random number table，42 cases in each group.The three groups were intramuscularly injected by 20，40，60mg/d of P.The serum P andβ-HCG levels after treatment were compared among 3 groups.The cases number of full term pregnancy ......