中图分类号：542.2 文献标识 码：A 文章编号：1009_816X(2011)06_0425_04

    DOI:10.3969/j.issn.1009_816X.2011.06.04 The Efficacy of Percutaneous Transluminal Septal Myocardial Ablation on Hypertro phic Obstructive Cardiomyopathy. CHEN Yan，FU Guo_sheng. Zhejiang Hospital，Zhejiang 310013，China

    [Abstract] Objective To evaluate the short_term efficacy of percutaneous transl uminal septal myocardial ablation(PTSMA) on hypertrophic obstructive cardiomyopa thy(HOCM). Methods 28 patients with symptomatic HOCM underwent PTSMA by Sigwart method were selected from November 2005 to Vebruary 2009,.The pressure gradient of left ventricular out floow tract (LVOTG)、thickness of septal myocardium (IVS )、width of left ventricular out floow tract (LVOT)、ejection fraction (EF) and electrocardiograms (ECG) were measured before and 1 month after PTSMA. Results P TSMA was performed 28 patients, the average alcohol injected into Septal branch was 2.46mL; the average LVOTPG before operation was (67.73±33.62)mmHg, and after operation it reduced to (29.50±25.67)mmHg (P<0.01) and IVS was(2 4.72±6.51)mm and(22.26±5.92)mm respectively (P<0.01). 5 patients had transitory II I°atrio_ventricular block (AVB) during operation, new_onset complete right bran ch block (CRBB) was found in 12 patients and all of them were persistent,all the clinical symptoms were relieved more or less. Conclusions PTSMA could significanty reduce LVOTG and the thickn ess of septal moyocardium. ......