【摘要】" 目的" 探讨羟考酮与氢吗啡酮对比，在经尿道前列腺切除术后的镇痛效果。方法" 选取2021年5月- 2024年5月医院收治的87例需要进行经尿道前列腺切除术的患者，根据组间基线资料均衡可比的原则，采用随机数字表法分为羟考酮组(n=44)和氢吗啡酮组(n=43)，羟考酮组术后给予羟考酮，氢吗啡酮组术后给予氢吗啡酮。比较两组患者术后1、2天镇痛效果、认知功能、术后麻醉情况及不良事件发生率。结果" 两组患者术后第2天视觉模拟评分法(VAS)评分、蒙特利尔认知评估量表(MoCA)评分均低于术后1天，但组间术后第1、2天的VAS评分及MoCA评分差异均无统计学意义(Pgt;0.05)。两组患者在麻醉恢复时间、苏醒时间及不良事件发生率比较，差异均无统计学意义(Pgt;0.05)。结论" 在同样的麻醉恢复情况下，羟考酮与氢吗啡酮在经尿道前列腺切除术后镇痛应用效果均较好，能够降低患者疼痛情况，恢复认知功能，且安全性较高。

    【关键词】" 羟考酮；氢吗啡酮；经尿道前列腺切除术；镇痛

    中图分类号" R699.8" "文献标识码" A" " 文章编号" 1671-0223(2025)03--03

    Comparison of analgesic effects of oxycodone and hydromorphone after transurethral resection of the prostate" Mao Kai， Shi Ke. Department of Anesthesiology， the Second Affiliated Hospital of Hubei University of Science and Technology， Xianning 437100， China

    【Abstract】" Objective To explore the analgesic effects of oxycodone and hydromorphone after transurethral resection of the prostate. Methods" A total of 87 patients who needed transurethral resection of the prostate and were admitted to the hospital from May 2021 to May 2024 were selected. According to the principle of balanced and comparable baseline data between groups ......