【摘要】" 基于瞬时弹性成像的肝脏硬度测定作为一项无创肝纤维化测定技术，目前在临床上被广泛应用。有研究证明，肝脏硬度测定可以准确预测慢性肝病患者临床显著性门静脉高压及高危静脉曲张。近年来脾脏硬度测定作为一项新兴的诊断技术，相比肝脏硬度其预测门静脉高压及相关并发症的准确性更高。研究旨在介绍基于瞬时弹性成像肝脏硬度测定及脾脏硬度测定在慢性肝病患者中预测临床显著性门静脉高压及高危静脉曲张的应用进展，从而帮助临床医师减少无意义的肝静脉压力梯度测定及内镜等侵入性操作，进而更高效地评估肝硬化患者病情并改善预后。

    【关键词】" 肝硬化；门静脉高压；食管胃静脉曲张；肝脏硬度测定；脾脏硬度测定

    中图分类号" R575.2" "文献标识码" A" " 文章编号" 1671-0223(2025)09--05

    Research status on predicting clinically significant portal hypertension and high-risk varices based on transient elastography" Hu Han.Graduate School， Zhejiang Chinese Medical University， Hangzhou 310053， China

    【Abstract】" Measurement of liver stiffness using transient elastography， as a non-invasive technique for assessing liver fibrosis， is now widely applied in clinical practice. Studies have shown that liver stiffness measurement can accurately predict clinically significant portal hypertension and high-risk esophageal varices in patients with chronic liver disease. In recent years， spleen stiffness measurement has emerged as a novel diagnostic technique， with some studies suggesting that， compared to liver stiffness ......