作者单位：530000" 广西省南宁市，广西中医药大学附属瑞康医院胃肠外科

    *通讯作者

    【摘要】" 胃肠道肿瘤(如结直肠癌、胃癌)多发于中老年人群，不仅对患者的生活质量产生巨大影响，还给患者及其家属带来巨大的心理及经济负担。目前其治疗手段主要以手术和放化疗为主，但仍存在复发的可能。双硫死亡是一种全新的细胞程序性死亡方式，对胃肠道肿瘤的发生发展起关键作用，也为防治胃肠道肿瘤提供了新的契机。深入研究双硫死亡与胃肠道肿瘤的关系，可为胃肠道肿瘤的治疗提供新思路。

    【关键词】" 结直肠癌；胃癌；双硫死亡

    中图分类号" R735.2" " 文献标识码" A" " 文章编号" 1671-0223(2024)08--03

    Research progress of disulfide death in the gastrointestinal tract" Yan Kaiwen， Huang Lizhe. Department of Gastroenterology， Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine， Nanning 530000， China

    【Abstract】" As a frequent disease in middle-aged and elderly people， gastrointestinal tumors(colorectal cancer and" gastric cancer) not only bring problems to patients， but also bring huge psychological and economic burdens to their families. At present， its treatment methods are mainly surgery and radiotherapy and chemotherapy， but there is still the possibility of recurrence. Disulfide death is a new pathway of programmed cell death， which plays a key role in the occurrence and development of gastrointestinal tumors and provides new opportunities for the prevention and treatment of gastrointestinal tumors. A further study of the relationship between disulfide death and gastrointestinal tumors could provide new ideas for the treatment of gastrointestinal tumors. ......