脓毒症动物模型制作及评价(5)
[29] Deitch EA.Rodent models of intra-abdominal infection[J]. Shock, 2005, 24 suppl 1:S19-S23.
[30] Remick DG, Newcomb DE, Bolgos GL, et al. Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture[J]. Shock, 2000, 13(2):110-116.
[31] Brealey D, Karyampudi S, Jacques TS, et al. Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure[J]. Am J Physiol Regul Integr Comp Physiol, 2004, 286(3):491-497.
, 百拇医药
[32] Eichacker PQ, Parent C, Kalil A, et al. Risk and the efficacy of antiinflammatory agents: Retrospective and confirmatory studies of sepsis[J]. Am J Respir Crit Care Med, 2002, 166(9):1197-1205.
[33] Piper RD, Cook DJ, Bone RC, et al, Introducing critical appraisal to studies of animal models investigating novel therapies insepsis[J]. Crit Care Med, 1996, 24(12):2059-2070.
[34] Copeland S, Warren HS, Lowry SF, et al. Acute inflammatory response to endotoxin in mice and humans[J]. Clin Diagn Lab Immunol, 2005, 12(1):60-67.
, 百拇医药
[35] Martich GD, Boujoukos AJ, Suffredini AF. Response of man to endotoxin[J]. Immunobiology, 1993, 187(3):403-416.
[36] Esmon CT.Why do animal models (sometimes) fail to mimic human sepsis? [J].Crit Care Med, 2004, 32 suppl 5:S219-S222.
[37] Padkin A, Goldfrad C, Brady AR, et al. Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland[J]. Crit Care Med, 2003, 31(9):2332-2338.
, http://www.100md.com
[38]Turnbull IR, Wlzorek JJ, Osborne D, et al. Effects of age on mortality and antibiotic efficacy in cecal ligation and puncture[J]. Shock, 2003, 19(4):310-313.
[39] Chorinchath BB, Kong LY, Mao L, et al. Age-associated differences in TNF-alpha and nitric oxide production in endotoxic mice[J]. J Immunol, 1996,156(4):1525-1530.
[40] Tateda K, Matsumoto T, Miyazaki S, et al. Lipopolysaccharide-induced lethality and cytokine production in aged mice[J]. Infect Immun, 1996, 64(3):769-774.
, 百拇医药
[41] Martin GS, Mannino DM, Eaton S, et al. The epidemiology of sepsis in the United States from 1979 through 2000[J]. N Engl J Med, 2003, 348(16):1546-1554.
[42] Knoferl MW, Angele MK, Diodato MD, et al. Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis[J]. Ann Surg, 2002, 235(1):105-112.
[43] Kher A, Wang M, Tsai BM, et al. Sex differences in the myocardial inflammatory response to acute injury[J]. Shock, 2005, 23(1):1-10.
, 百拇医药
[44] Esper AM, Moss M, Lewis CA, et al. The role of infection and comorbidity: Factors that influence disparities in sepsis[J]. Crit Care Med, 2006, 34(10):2576-2582.
[45] 高晓刚,陈德昌. 动物模型在脓毒症研究中的意义[J]. 中国急救医学,2006,26(10):685-686.
(收稿日期:2012-07-04)
(本文编辑:邵菊芳)
DOI:10.3760/cma.j.issn.1671-0282.2013.02.026
作者单位:100020 北京,首都医科大学附属北京朝阳医院急诊科
通信作者:李春盛 ,Email: Lcscyyy@sohu.com
P215-P218
, http://www.100md.com(吴彩军 李春盛)
[30] Remick DG, Newcomb DE, Bolgos GL, et al. Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture[J]. Shock, 2000, 13(2):110-116.
[31] Brealey D, Karyampudi S, Jacques TS, et al. Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure[J]. Am J Physiol Regul Integr Comp Physiol, 2004, 286(3):491-497.
, 百拇医药
[32] Eichacker PQ, Parent C, Kalil A, et al. Risk and the efficacy of antiinflammatory agents: Retrospective and confirmatory studies of sepsis[J]. Am J Respir Crit Care Med, 2002, 166(9):1197-1205.
[33] Piper RD, Cook DJ, Bone RC, et al, Introducing critical appraisal to studies of animal models investigating novel therapies insepsis[J]. Crit Care Med, 1996, 24(12):2059-2070.
[34] Copeland S, Warren HS, Lowry SF, et al. Acute inflammatory response to endotoxin in mice and humans[J]. Clin Diagn Lab Immunol, 2005, 12(1):60-67.
, 百拇医药
[35] Martich GD, Boujoukos AJ, Suffredini AF. Response of man to endotoxin[J]. Immunobiology, 1993, 187(3):403-416.
[36] Esmon CT.Why do animal models (sometimes) fail to mimic human sepsis? [J].Crit Care Med, 2004, 32 suppl 5:S219-S222.
[37] Padkin A, Goldfrad C, Brady AR, et al. Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland[J]. Crit Care Med, 2003, 31(9):2332-2338.
, http://www.100md.com
[38]Turnbull IR, Wlzorek JJ, Osborne D, et al. Effects of age on mortality and antibiotic efficacy in cecal ligation and puncture[J]. Shock, 2003, 19(4):310-313.
[39] Chorinchath BB, Kong LY, Mao L, et al. Age-associated differences in TNF-alpha and nitric oxide production in endotoxic mice[J]. J Immunol, 1996,156(4):1525-1530.
[40] Tateda K, Matsumoto T, Miyazaki S, et al. Lipopolysaccharide-induced lethality and cytokine production in aged mice[J]. Infect Immun, 1996, 64(3):769-774.
, 百拇医药
[41] Martin GS, Mannino DM, Eaton S, et al. The epidemiology of sepsis in the United States from 1979 through 2000[J]. N Engl J Med, 2003, 348(16):1546-1554.
[42] Knoferl MW, Angele MK, Diodato MD, et al. Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis[J]. Ann Surg, 2002, 235(1):105-112.
[43] Kher A, Wang M, Tsai BM, et al. Sex differences in the myocardial inflammatory response to acute injury[J]. Shock, 2005, 23(1):1-10.
, 百拇医药
[44] Esper AM, Moss M, Lewis CA, et al. The role of infection and comorbidity: Factors that influence disparities in sepsis[J]. Crit Care Med, 2006, 34(10):2576-2582.
[45] 高晓刚,陈德昌. 动物模型在脓毒症研究中的意义[J]. 中国急救医学,2006,26(10):685-686.
(收稿日期:2012-07-04)
(本文编辑:邵菊芳)
DOI:10.3760/cma.j.issn.1671-0282.2013.02.026
作者单位:100020 北京,首都医科大学附属北京朝阳医院急诊科
通信作者:李春盛 ,Email: Lcscyyy@sohu.com
P215-P218
, http://www.100md.com(吴彩军 李春盛)