急性心肌梗死患者冠状动脉病变程度的危险因素分析(1)
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[摘要] 目的 探讨不同危险因素与急性心肌梗死患者冠状动脉病变程度之间的关系。方法 选择251例确诊的急性心肌梗死患者,根据冠状动脉造影结果分为单支病变组、双支病变组和多支病变组,对3组患者的心血管危险因素进行比较分析。结果 双支病变组中高血压和血脂代谢紊乱患者比例较单支病变组明显增高(P<0.05);多支病变组中血脂代谢紊乱患者比例较单支病变组明显增高,糖尿病患者比例较双支病组明显增高(均P<0.05)。结论 高血压、血脂代谢紊乱和糖尿病与急性心肌梗死患者冠状动脉病变程度密切相关。
[关键词] 急性心肌梗死;冠状动脉病变;危险因素
[中图分类号] R541.1[文献标识码] A[文章编号] 1671-7562(2009)04-0277-03
Relationship of risk factors with the extent of the coronary lesions among patients with acute myocardial infarction
CHEN Zhong-pu1,CHEN Zhong2,MA Gen-shan2,FANG Ying1,SHEN Cheng-xing2,TANG Cheng-chun2,FENG Yi2
(1.College of Medicine,Southeast University,Nanjing 210009,China;2.Department of Cardiology,Zhongda Hospital,Southeast University,Nanjing 210009,China)
Abstract:Objective To discuss the relationship of risk factors and the extent of the coronary lesions among patients with acute myocardial infarction (AMI).Methods Two hundreds and fifty-one patients with documented AMI were enrolled.According to the results of coronary angiography,patients were divided into single-vessel group,two-vessel group,and multi-vessel diseased group.Risk factors among these three groups were analyzed.Results In the two-vessel disease group,the percentages of hypertension and dyslipidemia were higher than that in the single-vessel group;in the multi-vessel diseased group,the percentage of dyslipidemia was higher than that in the single-vessel group and the proportion of diabetes were higher than in other two groups.Conclusion Clinical risk factors are closely associated with the extent of coronary lesions among patients with AMI.
Key words:acute myocardial infarction;coronary artery disease;risk factors
(Modern Medical Journal,2009,37:277-279)
冠心病(CAD)是一种常见的心血管疾病。急性心肌梗死(AMI)是CAD的临床危重类型,致死、致残率高,对人类健康危害极大。AMI发病因素复杂,其最主要的独立因素包括高血压、血脂代谢紊乱和糖尿病等。本研究采用冠状动脉造影进行冠状动脉病变程度评估,分析251例AMI患者临床危险因素与冠状动脉病变程度间的关系,为临床防治提供参考。
1 对象与方法
1.1 研究对象
选择2003年8月至2008年3月在东南大学附属中大医院心血管内科住院并依据WHO制定的AMI诊断标准确诊为AMI并行冠状动脉造影术患者251例,以冠状动脉狭窄≥50%的支数为依据将研究对象分为3组:单支病变组105例、双支病变组60例和多支病变组(病变支数≥3支)86例。患者均有完整的病历资料及冠状动脉造影结果。
1.2 研究方法
根据患者临床资料列出危险因素为:(1)高血压;(2)血脂代谢紊乱;(3)糖尿病;(4)吸烟;(5)饮酒;(6)家族史 ......
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