碳酸锂联合帕罗西治疗抑郁症的有效性与安全性研究
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摘要：目的：探讨研究碳酸锂联合帕罗西治疗抑郁症的有效性与安全性。方法：选取90例难治性精神分裂症患者为研究对象，随机分为观察组和对照组各45例，对照组采用帕罗西汀治疗，观察组采用碳酸锂联合帕罗西汀治疗。治疗后采用汉密尔顿抑郁量表(HAMD) 和抗抑郁剂不良反应量表(Asberg)，分别评定两组疗效和不良反应。结果：治疗6周、8周后，观察组患者HAMD减分率(33.54±10.36、49.46±17.38)；治疗8周察组Asberg抗抑郁剂不良反应量表评分(4.63±2.02)、发生震颤、胃肠道反应等药物不良反应(13.33%)明显低于对照组。结论：碳酸锂联合帕罗西治疗抑郁症疗效好，安全性高，值得临床推广。
关键词：碳酸锂帕罗西汀难治性抑郁症
Doi:10.3969/j.issn.1671-8801.2014.08.033Lithium carbonate combined paro west efficacy and safety of the treatment of depression research
Wu Huaqiao
Abstract:Objective:To study the lithium carbonate combined paro west efficacy and safety of the treatment of depression.Methods:Select 90 cases as the research object,in patients with refractory schizophrenia were randomly divided into observation group and control group 45 cases,control group treated with paroxetine,observation group with lithium carbonate with paroxetine therapy.After treatment with Hamilton depression scale (HAMD) and antidepressants adverse reaction scale (Asberg),to evaluate the two groups of curative effect and adverse reactions,respectively ......
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