基于数据挖掘及网络药理学探讨袁金声教授治疗高血压的用药规律及

基于数据挖掘及网络药理学探讨袁金声教授治疗高血压的用药规律及作用机制

http://www.100md.com 2025年9月28日中西医结合心脑血管病杂志 2025年第17期

     ExplorationoftheMedicationRulesandMechanismofProfessorYuanJinshenginTreatingHypertension BasedonClinicalData SHUHua1，WUFeng2，WANGChangme，ZHANG Miao1，YANGChengyong2，JINAilin，SHANGGUANFahui，XIEMin LI Zhengsheng1，LIAO Yue1，WANG Qian1

    1.SecondAfliatedHospitalofGuizhouUniversityofTraditionalChineseMedicine，Guizhou550o01，Guiyang，China，E-mal490135529@qq.com; 2.People's Hospital of Dafang; 3.Guizhou University of Traditional Chinese Medicine

    AbstractObjective：ToexploreProfessorYuanJinsheng'smedicationpatesfortreatinghypertensionandthemechanismof hecore formulathroughthetraditional Chinesemedicineinheritancecomputingplatfom.Methods：TheprescriptionsofYuanJinshengforthe treatmentofhypertensionwerecolectedandanalyzedthroughthetraditionalChinesemedicineinheritancecomputingplatform.The actionof thecoreprescriptionsforthetreatmentof hypertensionwasexploredusingnetworkpharmacologyresearchmethodsand mutipledatabases.Tekeyomponentsandtargetproteinswerereversevalidatedwiththeelpofmoleculardockingsoftareesults：A totalof623prescrptions，uding253CineserbalmedicineswereinedThereere16ighractiveingredients ......

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