基于网络药理学和分子对接探讨益气活血方治疗糖尿病合并冠心病的作用机制
TheMechanismofYqi HuoxueRecipeintheTreatmentofDiabetes MelltusComplicatedwithCoronary HeartDisease Basedon Vetwork Pharmacology and Molecular Docking 3UNFengfeng1,LICaiping2,, SONG Lijuan1,81.ShanxiUniversityofCineeMedicine,Jinzong309,Shani,China;2heFirstClinicalColegeofSaniUiversityfCine Medicine,TheAfliatedHospitalofShanxi UniversityofChineseMedicine,TaiyuanO3024,Shanxi,China;3.ShaniKeyLaboratoryof Innovative Drugs for Major Diseases Based on Inflammatory Response,Jinzhong O30619,Shanxi,ChinaCorrespondingAuthor LlCaiping,E-mail:licaiping06 @ 163.com
AbstractObjective:TostudyandverifytemechanismofYiqiHuoxueRecipeintreatingdiabetesmeliuscomplicatedwithcoronary heartdiseasebasedonnetworkpharmacologyandmoleculardockingtechnologyMethods:Theefectivecomponentsandactiontargets oftheYiqiHuoxueRecipewerecolectedthroughtheTraditionalChineseMedicineSystemPharmacologyDataAnalysisPlaform (TCMSP).ScreeningwasconductedusingtheUniProtdatabase,andthenintersectiongenescreeningwascariedoutwiththedisease targetsofdiabetescomplicatedwithcoronaryheartdiseaseobtainedthroughtheGeneCardsdatabase ......
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