【第一作者简介】秦瑛键(1971-)，女，主管检验师，主要从事生殖医学

    检验方向的研究。

    【摘要】目的：进一步研究各类抗精子抗体对生育的影响。方法：临床应用ELISA法检测血清抗精子抗体。结果：ELISA法操作简单、方便迅速、灵敏性高、特异性强、准确性强、临床效果好。结论：深入研究生殖相关抗原对于了解生殖过程中的信号传导机理和解决不孕不育中的免疫病理具有现实意义。

    【关键词】免疫性不育；精子抗原；血清抗精子抗体；ELISA法

    Detection of serum anti-sperm antibodies by elisa methodQIN Yingjian, WANG Yan. Reproductive Center of Guilin Maternal and Child Healthcare Hospital, Guilin 541001, China

    【Abstract】To further study the impact of various anti-sperm antibodies on fertility. Methods: ELISA was used in clinical settings to detect serum anti-sperm antibodies. Results: With simple and convenient operation, ELISA was of high sensitivity, specificity and accuracy, exerting good clinical effect. Conclusions: An in-depth study of fertility-relevant antigens is of significance to understand the signal transduction mechanism in reproductive process and address the immunopathogenesis for infertility.

    【Key words】Immunological infertility; Sperm antigens; Serum anti-sperm antibody; ELASA

    【中图分类号】R698+.2【文献标志码】A

    近年来 ......