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盐酸羟考酮控释片联合氟哌噻吨美利曲辛片对恶性肿瘤患者的治疗研究(1)
http://www.100md.com 2018年9月1日 《健康必读·下旬刊》 2018年第9期
     【摘 要】目的 研究盐酸羟考酮控释片联合氟哌噻吨美利曲辛片治疗恶性肿瘤患者的疗效。 方法 观察对象为我院100例恶性肿瘤患者,患者根据自愿原则加入对照组或观察组,各50例。分别采用盐酸羟考酮、盐酸羟考酮联合氟哌噻吨美利曲辛片的方案治疗对照组与观察组,对两组患者治疗后效果进行评估,还需记录两组患者治疗后的不良反应发生情况。结果 观察组显效和有效例数共为47例(94.00%),显著优于对照组显效和有效例数37例(74.00%),且两组患者治疗后均有少数患者出现不良反应,对照组患者共出现12例(20.00%),观察组患者仅出现4例(8.00%),比较两组患者不良反应发生率,发现观察组患者不良反应发生率(8.00%)显著低于对照组患者(20.00%),以上数据均经过统计,发现存在显著差异(P<0.05)。结论 针对恶性肿瘤患者的治疗,盐酸羟考酮控释片联合氟哌噻吨美利曲辛片的方案具有显著效果,值得在临床中广泛使用和推广。

    【关键词】盐酸羟考酮控释片;氟哌噻吨美利曲辛片;恶性肿瘤;

    Abstract Objective to study the efficacy of oxycodone hydrochloride controlled-release tablets combined with Flupentixol and Melitracen Tablets in the treatment of patients with malignant tumor. Methods a total of 100 patients with malignant tumor in our hospital were selected. The patients were divided into 50 groups according to the principle of voluntariness. Hydrochloric oxycodone hydrochloride and hydrochloric oxycodone combined with Flupentixol and Melitracen Tablets were used to treat the control group and the observation group. The effect of the two groups after treatment was evaluated, and the adverse reaction of two groups of patients after treatment was also recorded. Results the number of effective and effective cases in the observation group was 47 cases (94%), which was significantly better than the control group and 37 cases (74%), and the two groups of patients had adverse reactions after treatment, 12 cases (20%) in the control group, and 4 cases (8%) in the observation group, and two groups of poor patients.The incidence of reaction was found in the observation group (8%), which was significantly lower than that of the control group (20%), and the above data were statistically significant (P<0.05). Conclusion the combination of oxycodone hydrochloride and Flupentixol and Melitracen Tablets has significant effect on the treatment of patients with malignant tumor. It is worth widely using and popularizing in the clinic.

    【中圖分类号】R730 【文献标识码】A 【文章编号】1672-3783(2018)09-03--01

    前言

    医学资料表明,恶性肿瘤就是癌症的统称,恶性肿瘤发生的主要原因是人体内正常细胞长期接触化学、放射性物质,或感染了某些病毒后,局部组织细胞失去调控细胞正常生长的功能,就由正常细胞转变为癌细胞[1]。恶性肿瘤患者早期往往察觉不到症状,少数患者可能会出现疼痛、出血、皮肤肿块及溃疡等情况,但等到患者出现剧烈疼痛、贫血、水肿等机体衰竭现象,说明恶性肿瘤已经发展到晚期,治愈的几率很渺茫了。恶性肿瘤的多发性、复发性、转移速度快且转移部位难判断,导致医学上对它仍然束手无策,所以早期的发现、诊断和积极治疗非常重要。

    1 资料与方法

    1.1 一般资料

    观察对象为2016年6月至2017年6月在我院接受住院治疗的100例恶性肿瘤患者,患者根据自愿原则加入对照组或观察组,各50例。对照组中,23例男性,27例女性;最小年龄为23岁,最大年龄为51岁,平均年龄为42.55±4.58岁;其中,食管癌22例,乳腺癌20例,膀胱癌8例。观察组中,25例男性,25例女性;最小年龄为24岁,最大年龄为52岁,平均年龄为44.23±4.32岁;其中,食管癌20例,乳腺癌23例,膀胱癌7例。两组患者性别、年龄、病情等基本情况对比,无明显差异(P<0.05)。, http://www.100md.com(韩彬 冯丹 刘福)
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