肿瘤细胞侵袭转移机制的研究现状(4)
[24]Martin T A, Goyal A, Watkins G, et al. Expression of thetranscription factors snail, slug, and twist and their clinicalsignificance in human breast cancer. Ann Surg Oncol, 2005, 12(6):488～496
[25]Gavert N, Ben-Ze’ev A. Epithelial-mesenchymal transition and theinvasive potential of tumors. Trends Mol Med, 2008, 14(5): 199～209
[26]Yook J I, Li X Y, Ota I, et al. A Wnt-Axin2-GSK3beta cascaderegulates Snail1 activity in breast cancer cells. Nat Cell Biol, 2006, 8(12): 1398～1406
, http://www.100md.com
[27]Feldmann G, Dhara S, Fendrich V, et al. Blockade of hedgehogsignaling inhibits pancreatic cancer invasion and metastases: a newparadigm for combination therapy in solid cancers. Cancer Res,2007, 67(5): 2187～2196
[28]Huber M A, Azoitei N, Baumann B, et al. NF-kappaB is essentialfor epithelial-mesenchymal transition and metastasis in a model ofbreast cancer progression. J Clin Invest, 2004, 114(4): 569～581
[29]Gregory P A, Bracken C P, Bert A G, et al. MicroRNAs asregulators of epithelial-mesenchymal transition. Cell Cycle, 7 (20):3112～3118
, http://www.100md.com
[30]Burk U, Schubert J, Wellner U, et al. A reciprocal repressionbetween ZEB1 and members of the miR-200 family promotes EMTand invasion in cancer cells. EMBO Rep, 2008, 9(6): 582～589
[31]Bracken C P, Gregory P A, Kolesnikoff N, et al. A double-negativefeedback loop between ZEB1-SIP1 and the microRNA-200 familyregulates epithelial–mesenchymal transition. Cancer Res, 2008, 68(19): 7846～7854
[32]Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors intumour progression: an alliance against the epithelial phenotype?.Nature Rev Cancer, 2007, 7(6): 415～428
, http://www.100md.com
[33]Gregory P A, Bert A G, Paterson E L, et al. The miR-200 family andmiR-205 regulate epithelial to mesenchymal transition by targetingZEB1 and SIP1. Nature Cell Biol, 2008, 10(5): 593～601
[33]Park S M, Gaur A B, Lengyel E, et al. The miR-200 familydetermines the epithelial phenotype of cancer cells by targeting theE-cadherin repressors ZEB1 and ZEB2. Genes Dev, 2008, 22 (7):894～907
[34]Korpal M, Lee E S, Hu G, et al. The miR-200 family inhibitsepithelial-mesenchymal transition and cancer cell migration bydirect targeting of E-cadherin transcriptional repressors ZEB1 andZEB2. J Biol Chem, 2008, 283(22): 14910～14914
, http://www.100md.com
[35]Kong W, Yang H, He L, et al. MicroRNA-155 is regulated by thetransforming growth factor beta/Smad pathway and contributes toepithelial cell plasticity by targeting RhoA. Mol Cell Biol, 2008, 28(22): 6773～6784
[36]Martin S S, Ridgeway A G, Pinkas J, et al. A cytoskeleton-basedfunctional genetic screen identifies Bcl-xL as an enhancer ofmetastasis, but not primary tumor growth. Oncogene, 2004, 23(26):4641～4645
[37]Wang X, Belguise K, Kersual N, et al. Oestrogen signalling inhibitsinvasive phenotype by repressing RelB and its target BCL2. Nat CellBiol, 2007, 9(4): 470～478
[38]Mehlen P, Puisieux A. Metastasis a question of life or death. NatRev Cancer, 2006, 6(6): 449～458
[39]Hofmann U B, Houben R, Brocker E B, et al. Role of matrixmetalloproteinases in melanoma cell invasion. Biochimie, 2005, 87(3～4): 307～314, 百拇医药(赵文芳 贾永峰(通讯作者))
[25]Gavert N, Ben-Ze’ev A. Epithelial-mesenchymal transition and theinvasive potential of tumors. Trends Mol Med, 2008, 14(5): 199～209
[26]Yook J I, Li X Y, Ota I, et al. A Wnt-Axin2-GSK3beta cascaderegulates Snail1 activity in breast cancer cells. Nat Cell Biol, 2006, 8(12): 1398～1406
, http://www.100md.com
[27]Feldmann G, Dhara S, Fendrich V, et al. Blockade of hedgehogsignaling inhibits pancreatic cancer invasion and metastases: a newparadigm for combination therapy in solid cancers. Cancer Res,2007, 67(5): 2187～2196
[28]Huber M A, Azoitei N, Baumann B, et al. NF-kappaB is essentialfor epithelial-mesenchymal transition and metastasis in a model ofbreast cancer progression. J Clin Invest, 2004, 114(4): 569～581
[29]Gregory P A, Bracken C P, Bert A G, et al. MicroRNAs asregulators of epithelial-mesenchymal transition. Cell Cycle, 7 (20):3112～3118
, http://www.100md.com
[30]Burk U, Schubert J, Wellner U, et al. A reciprocal repressionbetween ZEB1 and members of the miR-200 family promotes EMTand invasion in cancer cells. EMBO Rep, 2008, 9(6): 582～589
[31]Bracken C P, Gregory P A, Kolesnikoff N, et al. A double-negativefeedback loop between ZEB1-SIP1 and the microRNA-200 familyregulates epithelial–mesenchymal transition. Cancer Res, 2008, 68(19): 7846～7854
[32]Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors intumour progression: an alliance against the epithelial phenotype?.Nature Rev Cancer, 2007, 7(6): 415～428
, http://www.100md.com
[33]Gregory P A, Bert A G, Paterson E L, et al. The miR-200 family andmiR-205 regulate epithelial to mesenchymal transition by targetingZEB1 and SIP1. Nature Cell Biol, 2008, 10(5): 593～601
[33]Park S M, Gaur A B, Lengyel E, et al. The miR-200 familydetermines the epithelial phenotype of cancer cells by targeting theE-cadherin repressors ZEB1 and ZEB2. Genes Dev, 2008, 22 (7):894～907
[34]Korpal M, Lee E S, Hu G, et al. The miR-200 family inhibitsepithelial-mesenchymal transition and cancer cell migration bydirect targeting of E-cadherin transcriptional repressors ZEB1 andZEB2. J Biol Chem, 2008, 283(22): 14910～14914
, http://www.100md.com
[35]Kong W, Yang H, He L, et al. MicroRNA-155 is regulated by thetransforming growth factor beta/Smad pathway and contributes toepithelial cell plasticity by targeting RhoA. Mol Cell Biol, 2008, 28(22): 6773～6784
[36]Martin S S, Ridgeway A G, Pinkas J, et al. A cytoskeleton-basedfunctional genetic screen identifies Bcl-xL as an enhancer ofmetastasis, but not primary tumor growth. Oncogene, 2004, 23(26):4641～4645
[37]Wang X, Belguise K, Kersual N, et al. Oestrogen signalling inhibitsinvasive phenotype by repressing RelB and its target BCL2. Nat CellBiol, 2007, 9(4): 470～478
[38]Mehlen P, Puisieux A. Metastasis a question of life or death. NatRev Cancer, 2006, 6(6): 449～458
[39]Hofmann U B, Houben R, Brocker E B, et al. Role of matrixmetalloproteinases in melanoma cell invasion. Biochimie, 2005, 87(3～4): 307～314, 百拇医药(赵文芳 贾永峰(通讯作者))