上皮间质转化与肿瘤侵袭转移(1)
上皮间质转化与肿瘤侵袭转移,上皮细胞间质转化(EMT),发生机制,肿瘤转移
[摘 要] 上皮细胞间质转化(epithelial-mesenchymal transitions,EMT)是由上皮细胞转换成为间质细胞并获得侵袭和迁移能力的过程,EMT的发生涉及到多个信号转导通路和复杂的分子机制。EMT与肿瘤细胞的侵袭和转移关系密切。[关键词] 上皮细胞间质转化(EMT);发生机制;肿瘤转移
[Abstract] Epithelial-mesenchymal transitions (EMT) is a process that epithelial cell layers lose polarity and acquire expression of mesenchymal components and manifestamigratory phenotype. The progress of EMT involves a number of signal transduction pathways and complex molecular mechanisms, EMT play an important role in tumor metastasis.
[Key words] epithelial-mesenchymal transitions; mechanisms; tumormetastasis
上皮细胞间质转化(epithelial-mesenchymal transitions ......
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