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血浆内皮素1水平与冠心病严重程度的相关性研究(1)
http://www.100md.com 2012年2月1日 秦梦婷 邱强
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     摘要:目的:探讨血浆内皮素1(ET-1)水平与冠心病严重程度的相关性。方法: 采用酶联免疫吸附法(ELISA)分别对急性冠脉综合征(ACS),稳定型心绞痛(SAP)及正常对照组的患者,进行血浆ET-1水平测定。结果: ACS组中血浆ET-1水平明显高于SAP和对照组(P<0.01), SAP组中ET-1高于对照组(P<0.05),差异有显著性意义,ET-1水平与冠心病严重程度呈正相关。结论 检测血浆内皮素1水平的变化可反映冠心病患者病情的严重程度。

    关键词:血浆内皮素-1;急性冠脉综合征;稳定型心绞痛 中国全科医学Abstract:Objective: To value the clinic relationship of endothelin-1(ET-1)with the severity of Coronary heart disease.Methods: We measured the plasma ET-1 viscosity of ACS patients group,SAP patients group, NORMAL patients group through the use of ELISA. Results: The ET-1 of ACS patients group was significantly higher than that of control group(p<0.05),which are significant differences between two groups of comparison.At the same time the level of ET-1 have positive correlation with the severity of Coronary heart disease.Conclusion: To measure the level of ET-1 can reflect the severity of Coronary heart disease.

    key words:ET-1;Acute Coronary syndrome;Stable angina pectoris.

    【中图分类号】R541 ......

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