摘要：目的：探讨单鼻孔经蝶入路外科治疗垂体瘤卒中的优点、治疗效果。方法：将患有垂体瘤且具有可比性的80例临床资料随机分为两组，每组40例，一组将其命名为经蝶组，即使用单鼻孔经蝶入路外科治疗垂体瘤卒中;另一组则命名为传统组，即使用传统的经颅手术治疗垂体瘤卒中。并观察手术情况，记录术中出血量、手术时间、住院时间以及术后随访观察记录有无尿崩症、脑脊液鼻漏等并发症的发生并进行总结比较分析。结果：80例垂体瘤患者都挺顺利的完成了手术。经蝶组的手术时间、住院时间比传统组短，术中出血量也比传统组少，另外脑脊液漏、尿崩症、视力恶化等并发症发生率也明显低于传统组，差异具有统计学意义(P<0.05)。结论：单鼻孔经蝶入路外科治疗垂体瘤卒中技术简便、手术创伤小、安全性高、治疗效果好、术后恢复快、并发症少。

    关键词：垂体肿瘤；单鼻孔经蝶入路；临床疗效

    Abstract:Objectives：Explore the advantages of a single nostril transsphenoidal surgical treatment of pituitary apoplexy, the therapeutic effect. Methods：Suffering from pituitary tumors and comparable 80 cases clinical data were randomly divided into two groups, each group of 40 cases, a group named transsphenoidal group, using a single nostril transsphenoidal Road, surgical treatment of pituitary tumor apoplexy;a group named for the traditional group, and that the use of transcranial surgical treatment of pituitary apoplexy. And observe the surgical situation, recorded intraoperative blood loss, operative time, hospital stay, and postoperative follow-up to observe the occurrence of the record with or without the complications of diabetes insipidus, cerebrospinal fluid rhinorrhea, and a summary of comparative analysis. Results：80 cases of pituitary tumor patients all came to a smooth completion of the surgery. Butterfly group, operative time, hospital stay is shorter than the traditional group, intraoperative blood loss was less than the traditional group, addition of cerebrospinal fluid leakage, diabetes insipidus, visual deterioration, the incidence of complications was significantly lower than the traditional group, the difference was significance (P<0.05). Conclusion：Single-nostril transsphenoidal surgical treatment of pituitary apoplexy technology is simple, minimally invasive, safe, effective treatment, rapid postoperative recovery, fewer complications. ......