甲状腺功能亢进症合并糖尿病患者检测肝功能价值研究(1)
DOI：10.16658/j.cnki.1672-4062.2019.05.053
甲状腺功能亢进症合并糖尿病患者检测肝功能
价值研究
王菲
长春中医药大学附属第三临床医院检验科，吉林长春 130000
[摘要] 目的 探讨甲状腺功能亢进症合并糖尿病患者检测肝功能的价值。方法 对2017年8月—2018年8月在该科进行肝功能检测的70例甲亢合并糖尿病患者与70例甲亢患者进行分析，并与65名健康体检者进行比较。结果 A组FPG显著高于B、C组(P<0.05)，A、B组FT3、FT4水平明显高于C组，TSH水平显著低于C组(P<0.05)，A、B组比较差异无统计学意义(P>0.05);A、B组ALT、AST、ALP、GGT、TB、DBIL水平较C组升高，ALB、TP较C组降低(P<0.05);A、B组比较差异无统计学意义(P>0.05)。结论 对甲亢合并糖尿病患者进行肝功能检测，有利于掌握患者病情，指导临床治疗和用药。
[关键词] 甲状腺功能亢进症;糖尿病;肝功能
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2019)03(a)-0053-02
Study on the Value of Liver Function in Patients with Hyperthyroidism Complicated with Diabetes
WANG Fei
Department of Clinical Laboratory， the Third Clinical Hospital Affiliated to Changchun University of Traditional Chinese Medicine， Changchun， Jilin Province， 130000 China
[Abstract] Objective To investigate the value of detecting liver function in patients with hyperthyroidism and diabetes. Methods 70 patients with hyperthyroidism complicated with diabetes mellitus and 70 patients with hyperthyroidism who underwent liver function tests in our department from August 2017 to August 2018 were analyzed and compared with 65 healthy subjects. Results The FPG of group A was significantly higher than that of group B and C(P<0.05). The levels of FT3 and FT4 in group A and group B were significantly higher than those in group C. The level of TSH was significantly lower than that in group C(P<0.05). There was no difference between group A and group B(P>0.05). The levels of ALT， AST， ALP， GGT， TB and DBIL in group A and group B were higher than those in group C， and ALB and TP were lower than those in group C(P<0.05). There was no difference between group A and group B(P>0.05). Conclusion The detection of liver function in patients with hyperthyroidism complicated with diabetes is beneficial to master the patient's condition and guide clinical treatment and medication.
[Key words] Hyperthyroidism; Diabetes; Liver function
甲状腺功能亢進症与糖尿病都是临床常见的代谢性疾病。甲亢虽不是糖尿病的并发症，但糖尿病更容易罹患甲亢，有报道表明[1]，糖尿病合并甲状腺疾病发生率为7.1%～51.6%。两种疾病有许多共同的遗传、免疫学基础，临床症状也有许多相似之处，对患者日常生活带来严重影响。此外，甲亢患者分泌过多的甲状腺素可引起多器官病理生理改变[2]，累及肝脏时引起肝肿大、肝功能异常，甚至肝硬化。为更好的了解甲亢合并糖尿病患者肝功能变化的意义，该研究对2017年8月—2018年8月在该科进行肝功能检测的70例甲亢合并糖尿病患者与70例甲亢患者进行分析，并与65名健康体检者进行比较，报道如下。
1 资料与方法
1.1 一般资料
选取在该科进行肝功能检测的甲亢合并糖尿病患者70例(A组)，男39例，女31例，年龄35～66岁，平均(49.7±2.6)岁，甲亢病程平均(4.6±1.1)年，糖尿病病程平均(7.9±1.5)年;进行肝功能检测的甲亢患者70例(B组)，男41例，女29例，年龄38～67岁，平均(48.6±2.3)岁，甲亢病程平均(4.8±0.7)年。另选取同期在该科进行检查的健康体检者65名(C组)，男35名，女30名，年龄30～65岁，平均(50.8±2.4)岁。该次研究患者均知情同意，经伦理委员会批准。患者一般资料比较差异无统计学意义(P>0.05)。, 百拇医药
甲状腺功能亢进症合并糖尿病患者检测肝功能
价值研究
王菲
长春中医药大学附属第三临床医院检验科，吉林长春 130000
[摘要] 目的 探讨甲状腺功能亢进症合并糖尿病患者检测肝功能的价值。方法 对2017年8月—2018年8月在该科进行肝功能检测的70例甲亢合并糖尿病患者与70例甲亢患者进行分析，并与65名健康体检者进行比较。结果 A组FPG显著高于B、C组(P<0.05)，A、B组FT3、FT4水平明显高于C组，TSH水平显著低于C组(P<0.05)，A、B组比较差异无统计学意义(P>0.05);A、B组ALT、AST、ALP、GGT、TB、DBIL水平较C组升高，ALB、TP较C组降低(P<0.05);A、B组比较差异无统计学意义(P>0.05)。结论 对甲亢合并糖尿病患者进行肝功能检测，有利于掌握患者病情，指导临床治疗和用药。
[关键词] 甲状腺功能亢进症;糖尿病;肝功能
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2019)03(a)-0053-02
Study on the Value of Liver Function in Patients with Hyperthyroidism Complicated with Diabetes
WANG Fei
Department of Clinical Laboratory， the Third Clinical Hospital Affiliated to Changchun University of Traditional Chinese Medicine， Changchun， Jilin Province， 130000 China
[Abstract] Objective To investigate the value of detecting liver function in patients with hyperthyroidism and diabetes. Methods 70 patients with hyperthyroidism complicated with diabetes mellitus and 70 patients with hyperthyroidism who underwent liver function tests in our department from August 2017 to August 2018 were analyzed and compared with 65 healthy subjects. Results The FPG of group A was significantly higher than that of group B and C(P<0.05). The levels of FT3 and FT4 in group A and group B were significantly higher than those in group C. The level of TSH was significantly lower than that in group C(P<0.05). There was no difference between group A and group B(P>0.05). The levels of ALT， AST， ALP， GGT， TB and DBIL in group A and group B were higher than those in group C， and ALB and TP were lower than those in group C(P<0.05). There was no difference between group A and group B(P>0.05). Conclusion The detection of liver function in patients with hyperthyroidism complicated with diabetes is beneficial to master the patient's condition and guide clinical treatment and medication.
[Key words] Hyperthyroidism; Diabetes; Liver function
甲状腺功能亢進症与糖尿病都是临床常见的代谢性疾病。甲亢虽不是糖尿病的并发症，但糖尿病更容易罹患甲亢，有报道表明[1]，糖尿病合并甲状腺疾病发生率为7.1%～51.6%。两种疾病有许多共同的遗传、免疫学基础，临床症状也有许多相似之处，对患者日常生活带来严重影响。此外，甲亢患者分泌过多的甲状腺素可引起多器官病理生理改变[2]，累及肝脏时引起肝肿大、肝功能异常，甚至肝硬化。为更好的了解甲亢合并糖尿病患者肝功能变化的意义，该研究对2017年8月—2018年8月在该科进行肝功能检测的70例甲亢合并糖尿病患者与70例甲亢患者进行分析，并与65名健康体检者进行比较，报道如下。
1 资料与方法
1.1 一般资料
选取在该科进行肝功能检测的甲亢合并糖尿病患者70例(A组)，男39例，女31例，年龄35～66岁，平均(49.7±2.6)岁，甲亢病程平均(4.6±1.1)年，糖尿病病程平均(7.9±1.5)年;进行肝功能检测的甲亢患者70例(B组)，男41例，女29例，年龄38～67岁，平均(48.6±2.3)岁，甲亢病程平均(4.8±0.7)年。另选取同期在该科进行检查的健康体检者65名(C组)，男35名，女30名，年龄30～65岁，平均(50.8±2.4)岁。该次研究患者均知情同意，经伦理委员会批准。患者一般资料比较差异无统计学意义(P>0.05)。, 百拇医药