[摘要] 目的 探究格列美脲联合二甲双胍治疗老年糖尿病患者的临床疗效。方法 将2018年1—12月时段内在该院治疗的老年糖尿病患者84例纳入研究，按照住院号单双数，将之分为两组，每组42例，对照组给予格列美脲治疗，观察组在此基础上加用二甲双胍，对比两组治疗效果及不良反应发生率。结果 治疗后，观察组FPG、2 hPG、HbAlc显著下降，显著低于对照组，两组数据差异有统计学意义(P<0.05);在不良反应发生率上，观察组为4.76%，低于对照组的11.90%，两组数据差异有统计学意义(P<0.05)。结论 格列美脲联合二甲双胍治疗老年糖尿病患者，安全高效，可有效降低血糖，值得采纳应用。

    [关键词] 格列美脲;二甲双胍;治疗;老年糖尿病患者;临床疗效

    [中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2019)07(b)-0063-02

    [Abstract] Objective To investigate the clinical efficacy of glimepiride combined with metformin in the treatment of elderly patients with diabetes mellitus. Methods Eighty-four elderly patients with diabetes mellitus who were treated in our hospital from January to December 2018 were enrolled in the study. According to the hospitalized singles ......