激光光凝联合抗VEGF药物不同时机治疗糖尿病视网膜病变的疗效比较(1)
[摘要] 目的 比较激光光凝联合抗VEGF药物(抗血管内皮生长因子药物)不同时机治疗糖尿病视网膜病变的疗效。方法 随机选取该院2019年1—12月收治的128例糖尿病视网膜病变患者为研究对象，采用随机数字的方法均分为观察组和对照组。对照组使用激光光凝后进行抗VEGF药物治疗，观察组使用抗VEGF药物治疗后进行激光光凝治疗，观察并统计两组患者的治疗有效率以及并发症发生率。结果 观察组患者的治疗有效率高于对照组(P<0.05)。观察组患者的并发症发生率低于对照组(P<0.05)。结论 对糖尿病视网膜病变患者使用抗VEGF药物治疗后进行激光光凝的临床治疗效果要优于使用激光光凝后进行抗VEGF药物治疗的临床治疗效果。
[关键词] 激光光凝;抗VEGF药物;不同时机;糖尿病视网膜病变;疗效
[中图分类号] R774 [文献标识码] A [文章编号] 1672-4062(2020)09(b)-0176-03
Comparison of the Efficacy of Laser Photocoagulation Combined with Anti-VEGF Drugs in the Treatment of Diabetic Retinopathy at Different Times
LYU Na
Department of Ophthalmology， Yueqing Youyi Orthopedics Hospital， Wenzhou， Zhejiang Province， 325600 China
[Abstract] Objective To compare the efficacy of laser photocoagulation combined with anti-VEGF drugs (anti-vascular endothelial growth factor drugs) in the treatment of diabetic retinopathy at different times. Methods 128 patients with diabetic retinopathy admitted to the hospital from January to December 2019 were randomly selected as the research objects， and these patients were divided into observation group and control group by random number method. The control group was treated with anti-VEGF drugs after laser photocoagulation， and the observation group was treated with laser photocoagulation after using anti-VEGF drugs. Observe and count the treatment efficiency and the incidence of complications of the two groups. Results The effective rate of treatment in the observation group was higher than that in the control group(P<0.05). The incidence of complications in the observation group was lower than that in the control group(P<0.05). Conclusion The clinical therapeutic effect of laser photocoagulation for patients with diabetic retinopathy treated with anti-VEGF drugs is better than the clinical therapeutic effect of laser photocoagulation with anti-VEGF drugs.
[Key words] Laser photocoagulation; Anti-VEGF drugs; Different timing; Diabetic retinopathy; Curative effect
糖尿病常見的微血管并发症之一就是糖尿病视网膜病变。患者的周围细胞变性、血管内皮细胞损伤、血糖过高以及血流量变化都会引起微血管眼底变化，使患者发生糖尿病视网膜病变，严重影响到了患者的日常生活以及生活质量，因此，必须对患者进行积极的治疗。目前在临床上对于糖尿病视网膜病变的治疗多使用视网膜激光光凝治疗以及抗VEGF药物治疗[1]。为了比较激光光凝联合抗VEGF药物在不同时机治疗糖尿病视网膜病变的疗效，提升患者的临床治疗效果，该院就2019年1—12月收治的128例糖尿病视网膜病变患者为研究对象，进行随机地对比研究并且全面分析了对比结果，现报道如下。
1 资料与方法
1.1 一般资料
随机选取该院收治的128例糖尿病视网膜病变患者为研究对象，采用随机数字的方法将这些患者均分为观察组和对照组。对照组64例(128眼)，其中男36例(72眼)，女28例(56眼);年龄42～69岁，平均年龄(53.52±5.62)岁。观察组64例(128眼)，其中男37例(74眼)，女27例(54眼);年龄在43～71岁，平均年龄(54.68±5.47)岁。两组一般资料差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(吕娜)
[关键词] 激光光凝;抗VEGF药物;不同时机;糖尿病视网膜病变;疗效
[中图分类号] R774 [文献标识码] A [文章编号] 1672-4062(2020)09(b)-0176-03
Comparison of the Efficacy of Laser Photocoagulation Combined with Anti-VEGF Drugs in the Treatment of Diabetic Retinopathy at Different Times
LYU Na
Department of Ophthalmology， Yueqing Youyi Orthopedics Hospital， Wenzhou， Zhejiang Province， 325600 China
[Abstract] Objective To compare the efficacy of laser photocoagulation combined with anti-VEGF drugs (anti-vascular endothelial growth factor drugs) in the treatment of diabetic retinopathy at different times. Methods 128 patients with diabetic retinopathy admitted to the hospital from January to December 2019 were randomly selected as the research objects， and these patients were divided into observation group and control group by random number method. The control group was treated with anti-VEGF drugs after laser photocoagulation， and the observation group was treated with laser photocoagulation after using anti-VEGF drugs. Observe and count the treatment efficiency and the incidence of complications of the two groups. Results The effective rate of treatment in the observation group was higher than that in the control group(P<0.05). The incidence of complications in the observation group was lower than that in the control group(P<0.05). Conclusion The clinical therapeutic effect of laser photocoagulation for patients with diabetic retinopathy treated with anti-VEGF drugs is better than the clinical therapeutic effect of laser photocoagulation with anti-VEGF drugs.
[Key words] Laser photocoagulation; Anti-VEGF drugs; Different timing; Diabetic retinopathy; Curative effect
糖尿病常見的微血管并发症之一就是糖尿病视网膜病变。患者的周围细胞变性、血管内皮细胞损伤、血糖过高以及血流量变化都会引起微血管眼底变化，使患者发生糖尿病视网膜病变，严重影响到了患者的日常生活以及生活质量，因此，必须对患者进行积极的治疗。目前在临床上对于糖尿病视网膜病变的治疗多使用视网膜激光光凝治疗以及抗VEGF药物治疗[1]。为了比较激光光凝联合抗VEGF药物在不同时机治疗糖尿病视网膜病变的疗效，提升患者的临床治疗效果，该院就2019年1—12月收治的128例糖尿病视网膜病变患者为研究对象，进行随机地对比研究并且全面分析了对比结果，现报道如下。
1 资料与方法
1.1 一般资料
随机选取该院收治的128例糖尿病视网膜病变患者为研究对象，采用随机数字的方法将这些患者均分为观察组和对照组。对照组64例(128眼)，其中男36例(72眼)，女28例(56眼);年龄42～69岁，平均年龄(53.52±5.62)岁。观察组64例(128眼)，其中男37例(74眼)，女27例(54眼);年龄在43～71岁，平均年龄(54.68±5.47)岁。两组一般资料差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(吕娜)