M2型丙酮酸激酶调控肿瘤生长的研究进展(4)
[21]JIANG Y， LI X， YANG W， et al. PKM2 regulates chromosome segregation and mitosis progression of tumor cells[J]. Mol Cell， 2014，53(1)：75-87.
[22]JIANG Y， WANG Y， WANG T， et al. PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells[J]. Nat Commun， 2014，5：5566.
[23]DHAR D K， OLDE D S， BRINDLEY J H， et al. Pyruvate kinase M2 is a novel diagnostic marker and predicts tumor progression in human biliary tract cancer[J]. Cancer， 2013，119(3)：575-585.
[24]魏路軍，任新友，徐林浩. E-cadherin、MUC1及PTEN与肿瘤转移相关性[J]. 青岛大学医学院学报， 2010，46(2)：183-188.
[25]UGUREL S， BELL N， SUCKER A， et al. Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma[J]. Int J Cancer， 2005，117(5)：825-830.
[26]ELIA S， MASSOUD R， GUGGINO G， et al. Tumor type M2-pyruvate-kinase levels in pleural fluid versus plasma in cancer patients： a further tool to define the need for invasive procedures[J]. Eur J Cardiothorac Surg， 2008，33(4)：723-727.
[27]SPODEN G A， MAZUREK S， MORANDELL D， et al. Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation[J]. Int J Cancer， 2008，123(2)：312-321.
[28]VANDER H M， CHRISTOFK H R， SCHUMAN E， et al. Identification of small molecule inhibitors of pyruvate kinase M2[J]. Biochem Pharmacol， 2010，79(8)：1118-1124., http://www.100md.com(周静 郑栋栋 卢玲)
[22]JIANG Y， WANG Y， WANG T， et al. PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells[J]. Nat Commun， 2014，5：5566.
[23]DHAR D K， OLDE D S， BRINDLEY J H， et al. Pyruvate kinase M2 is a novel diagnostic marker and predicts tumor progression in human biliary tract cancer[J]. Cancer， 2013，119(3)：575-585.
[24]魏路軍，任新友，徐林浩. E-cadherin、MUC1及PTEN与肿瘤转移相关性[J]. 青岛大学医学院学报， 2010，46(2)：183-188.
[25]UGUREL S， BELL N， SUCKER A， et al. Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma[J]. Int J Cancer， 2005，117(5)：825-830.
[26]ELIA S， MASSOUD R， GUGGINO G， et al. Tumor type M2-pyruvate-kinase levels in pleural fluid versus plasma in cancer patients： a further tool to define the need for invasive procedures[J]. Eur J Cardiothorac Surg， 2008，33(4)：723-727.
[27]SPODEN G A， MAZUREK S， MORANDELL D， et al. Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation[J]. Int J Cancer， 2008，123(2)：312-321.
[28]VANDER H M， CHRISTOFK H R， SCHUMAN E， et al. Identification of small molecule inhibitors of pyruvate kinase M2[J]. Biochem Pharmacol， 2010，79(8)：1118-1124., http://www.100md.com(周静 郑栋栋 卢玲)