[摘要] 目的 分析颈椎前路椎间盘切除减压植骨融合术(ACDF)治疗单节段颈椎病术后邻近节段退变(ASD)的发病率及危险因素。方法 回顾性分析2015年7月—2017年12月于我科行ACDF治疗单节段颈椎病病人60例的临床及影像学资料。结果 术后随访2年，按照影像学评定标准，ASD的发病率为23.3%(14/60)。ASD组和无退变组病人性别、椎管直径比较差异无统计学意义(P>0.05);ASD组病人年龄大于无退变组，术后Cobb角和钢板距邻近椎间隙之间的距离(PDD)均小于无退变组，差异有显著意义(t=-8.12～2.83，P<0.05)。结论 手术时年龄与ASD的发病率相关，PDD过小、颈椎生理曲度恢复不佳会导致ASD的发生。

    [关键词] 脊柱融合术;颈椎;椎间盘切除术;椎间盘退行性变;影响因素分析

    [中图分类号] R687.3;R681.5 [文献标志码] A [文章编号] 2096-5532(2020)05-0520-03

    doi：10.11712/jms.2096-5532.2020.56.164 [开放科学(资源服务)标识码(OSID)]

    [ABSTRACT] Objective To investigate the incidence rate of adjacent segment degeneration (ASD) after anterior cervical discectomy and fusion (ACDF) for single-segment cervical spondylosis and related risk factors. Methods A retrospective analysis was performed for the clinical and imaging data of 60 patients with single-segment cervical spondylosis who underwent ACDF in our department from July 2015 to December 2017. Results After 2 years of follow-up ......