BAEP对一氧化碳中毒续发脑病的预后检测(1)
[摘要]目的探讨一氧化碳中毒续发脑病的预后和BAEP的相关性。方法受视者轻轻闭眼，平卧床上，全身放松，记录电极置Cz点，参考电极置绘声测耳垂，接地电极置前额正中(FP2点)，极间阻抗小于5K 短声刺激，波宽0.1MS，声强80dBSL经耳机输出，单耳刺激，对侧耳白噪声50dB掩蔽，刺激频率10Hz，通频带100-3000Hz，信号自动叠加2048次，分析时间10ms，重复二次或三次以上示重复性。结果18例患者中，痊愈10例：各波潜伏期(PL)：双侧各波均正常(包括Ⅰ、Ⅱ、Ⅲ、Ⅴ)，其中2例一侧Ⅱ波分化差，波间潜伏期(IPL)均正常；显效4例：PL双侧正常，1例显示右侧Ⅰ~Ⅴ波分化差，另一例Ⅰ-Ⅲ波分化差， IPL均有一侧异常；好转2例： PL显示一侧分化差，波延迟， IPL均显示一侧延迟；未愈2例： PL显示一侧无诱发电位， IPL显示另一侧异常。结论一氧化碳中毒续发脑病的 BAEP异常与病情轻重程度呈一致关系，即BAEP异常越严重，预后越差，而BAEP正常或接近正常的患者预后较好。BAEP检测可做为评估本病病情，判断预后的一项有应用价值的客观指标之一。
, 百拇医药
关键词：一氧化碳中毒 续发脑病 BAEP
The evaluation of prognosis of delayed encephalopathy after CO poisoning by BAEP
Yang Xue-YingQI Jin-Xing
AnYang district hospital of HeNanAnYang455000
[Abstract]Aim： to explore the relationship between prognosis of delayed encephalopathy after CO poisoning and BAEP. Method： the test taker close eyes slightly with prostration position and relax throughly.The recording electrode was placed at Cz, while reference one placed at ipsilateral ear lobe and ground electrode at midline of forehead(FP2point). The short sound was used to stimulate the target ear through ear phone while the opposite one screened noisily. The impedance between poles is less than 5K. The wave widththe was 0.1MS.The intensity was 80dBSL.The frequency was 10HZ. The band pass is 100~3000Hz. Signal superposition was 1500 times.The analysis time is 10ms. Then repeated over 2 times in the same way to indicate reproducibility. Results： 10 was recovery of 18 cases,theⅠ、Ⅱ、Ⅲ、Ⅴ peak latency(PL) and inter-peak latency(IPL) was normal in all of which, Ⅱwave differentiation was worse in 2. 4 was excellent , peak latency(PL) was normal in all of which, Ⅰ~Ⅴdifferentiation was worse in one case, Ⅰ~Ⅲ differentiation was worse in another case and IPL was abnormal on either side in all.2 improved, both PL and IPL was delayed on either side and wave differentiation was worse in all.2 did not recover at all, PL revealed there was no evoked potential and IPL was abnormal on either side in all the 2 cases. Conclusions：The relationship between BAEP and severity of delayed encephalopathy after CO poisoning was concordant.The more significant BAEP abnormality,the worse prognosis was.The prognosis of cases in which BAEP is normal or close to normal is better. BAEP is a valuable one of objetive indexs to evaluate patient's condition and judge prognosis.
, 百拇医药
[Key word]BAEP;carbon monoxide poisoning;delayed encephalopathy
中图分类号：R595.1 文献标识码：B 文章编号：1672-5085(2007)4-0001-02
一氧化碳中毒续发脑病系指急性一氧化碳中毒病人经抢救恢复，经过数天到数周表现正常或接近正常的间歇期，而后又出现以痴呆为主的一组神经精神症状。有关本病的电生理改变，以脑电图报道较多，诱发电位报道较少。现将我们利用脑干听觉诱发电位(BAEP)对一氧化碳中毒续发脑病的预后检测结果报道如下。
1 资料与方法
1.1 一般资料
本组18例患者,男14例,女4例。年龄在27～54岁之间，均龄43.7岁。18例病人均为用煤炉取暖中毒所致。昏迷时间短者4小时，长者76小时。病人神志清醒后，在1～7天内恢复正常或接近正常。由此时起至再出现进行性“痴呆”症状的间歇期为16～68天，平均为35.7天。BAEP检测时间：在续发脑病症状出现20～40天检查。
1.2 方法
用日本光电公司生产的Neuropuck MEP—5200型诱发电位记录仪。实验设计符合国内外近年多采用的标准[1]，受视者轻轻闭眼，平卧床上，全身放松，记录电极置Cz点，参考电极置绘声测耳垂，接地电极置前额正中(FP2点)，极间阻抗小于5K 短声刺激，波宽0.1MS，声强80dBSL经耳机输出，单耳刺激，对侧耳白噪声50dB掩蔽，刺激频率10Hz，通频带100～3000Hz，信号自动叠加2048次，分析时间10ms，重复二次或三次以上示重复性。, http://www.100md.com(杨雪英 齐进兴)
, 百拇医药
关键词：一氧化碳中毒 续发脑病 BAEP
The evaluation of prognosis of delayed encephalopathy after CO poisoning by BAEP
Yang Xue-YingQI Jin-Xing
AnYang district hospital of HeNanAnYang455000
[Abstract]Aim： to explore the relationship between prognosis of delayed encephalopathy after CO poisoning and BAEP. Method： the test taker close eyes slightly with prostration position and relax throughly.The recording electrode was placed at Cz, while reference one placed at ipsilateral ear lobe and ground electrode at midline of forehead(FP2point). The short sound was used to stimulate the target ear through ear phone while the opposite one screened noisily. The impedance between poles is less than 5K. The wave widththe was 0.1MS.The intensity was 80dBSL.The frequency was 10HZ. The band pass is 100~3000Hz. Signal superposition was 1500 times.The analysis time is 10ms. Then repeated over 2 times in the same way to indicate reproducibility. Results： 10 was recovery of 18 cases,theⅠ、Ⅱ、Ⅲ、Ⅴ peak latency(PL) and inter-peak latency(IPL) was normal in all of which, Ⅱwave differentiation was worse in 2. 4 was excellent , peak latency(PL) was normal in all of which, Ⅰ~Ⅴdifferentiation was worse in one case, Ⅰ~Ⅲ differentiation was worse in another case and IPL was abnormal on either side in all.2 improved, both PL and IPL was delayed on either side and wave differentiation was worse in all.2 did not recover at all, PL revealed there was no evoked potential and IPL was abnormal on either side in all the 2 cases. Conclusions：The relationship between BAEP and severity of delayed encephalopathy after CO poisoning was concordant.The more significant BAEP abnormality,the worse prognosis was.The prognosis of cases in which BAEP is normal or close to normal is better. BAEP is a valuable one of objetive indexs to evaluate patient's condition and judge prognosis.
, 百拇医药
[Key word]BAEP;carbon monoxide poisoning;delayed encephalopathy
中图分类号：R595.1 文献标识码：B 文章编号：1672-5085(2007)4-0001-02
一氧化碳中毒续发脑病系指急性一氧化碳中毒病人经抢救恢复，经过数天到数周表现正常或接近正常的间歇期，而后又出现以痴呆为主的一组神经精神症状。有关本病的电生理改变，以脑电图报道较多，诱发电位报道较少。现将我们利用脑干听觉诱发电位(BAEP)对一氧化碳中毒续发脑病的预后检测结果报道如下。
1 资料与方法
1.1 一般资料
本组18例患者,男14例,女4例。年龄在27～54岁之间，均龄43.7岁。18例病人均为用煤炉取暖中毒所致。昏迷时间短者4小时，长者76小时。病人神志清醒后，在1～7天内恢复正常或接近正常。由此时起至再出现进行性“痴呆”症状的间歇期为16～68天，平均为35.7天。BAEP检测时间：在续发脑病症状出现20～40天检查。
1.2 方法
用日本光电公司生产的Neuropuck MEP—5200型诱发电位记录仪。实验设计符合国内外近年多采用的标准[1]，受视者轻轻闭眼，平卧床上，全身放松，记录电极置Cz点，参考电极置绘声测耳垂，接地电极置前额正中(FP2点)，极间阻抗小于5K 短声刺激，波宽0.1MS，声强80dBSL经耳机输出，单耳刺激，对侧耳白噪声50dB掩蔽，刺激频率10Hz，通频带100～3000Hz，信号自动叠加2048次，分析时间10ms，重复二次或三次以上示重复性。, http://www.100md.com(杨雪英 齐进兴)