The Ca2+Antagonizing Effect of Chinese Cobra Venom(3)
2 Results
2.1 Identification of macrophage-derived foam cells
With the macrophages incubated in OLDL, the intracellular cholesterol increased significantly (see table 1), and the constituent ratio of cholesterol esters in total cholesterol reached more than 50% (see figure 1). This was consistent with the cytological characteristics of foam cells in atherosclerotic plaques.
Table 1 showed the intracellular cholesterol contents in different groups of C57BL/6J mouse peritoneal macrophages. (1) RPMI1640 medium with 10% fetal calf serum as control; (2) Control medium with 10mg/L OLDL; (3) Control medium with 10mg/L OLDL + 10mg/L CCVF. *P, 百拇医药(谭健苗 杨向东 姜志胜 李 亮)
2.1 Identification of macrophage-derived foam cells
With the macrophages incubated in OLDL, the intracellular cholesterol increased significantly (see table 1), and the constituent ratio of cholesterol esters in total cholesterol reached more than 50% (see figure 1). This was consistent with the cytological characteristics of foam cells in atherosclerotic plaques.
Table 1 showed the intracellular cholesterol contents in different groups of C57BL/6J mouse peritoneal macrophages. (1) RPMI1640 medium with 10% fetal calf serum as control; (2) Control medium with 10mg/L OLDL; (3) Control medium with 10mg/L OLDL + 10mg/L CCVF. *P, 百拇医药(谭健苗 杨向东 姜志胜 李 亮)