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探讨喹诺酮类药物的不良反应及药物间的相关作用
http://www.100md.com 2008年2月1日 《中外健康文摘·临床医师》 2008年第2期
     【中图分类号】R917【文献标识码】A【文章编号】1672-5085(2008)02-0141-02

    【摘要】喹诺酮类是人工合成的含4-喹诺酮基结构,对DNA螺旋酶具有选择性抑制作用的抗菌药物。此类药物广泛用于泌尿生殖系统疾病、胃肠疾病、呼吸道以及皮肤组织的革兰阴性细菌感染的治疗。目前临床常用喹诺酮基本结构上连有氟原子的衍生物,其使用过程中出现的不良反应以及其他诸多问题时有发生和屡见报道。本文就不良反应、药物相互作用、用药注意等阐述喹诺酮类药物的使用注意事项,供临床参考使用。

    【关键词】喹诺酮类药物;不良反应;相关作用

    The discussioncarbostyril ketones medicine not good responded and correlation between the medicine Zhang Xiuyun1 Lan Ying qiu2

    【Abstract】 Carbostyril ketones is the manual synthesis contains 4-carbostyril structures, has the selectivity inhibitory action to the DNA spiral enzyme the antibiotics. This kind of medicine widely uses in the leather blue negative bacterium infection treatment which the uropoiesis reproductive system disease, the stomach and intestines disease, the respiratory tract as well as the skin organizes. At present in the clinical commonly usedcarbostyril alkone basic structure the company has the fluorine atom the derivative, in its use process appears not good responded and all that many questions sometimes occurs with repeatedly sees the report. This article not good responded, the medicine mutually affects, uses elaborationcarbostyril ketones medicine the and so on medicine attention use matters needing attention, for clinical reference use. ......

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