摘要：P-糖蛋白是一种膜转运蛋白，可将药物由胞液泵出胞外，从而降低了药物的生物利用度。现将P-糖蛋白影响药物吸收的特点及相关内容作一论述。

    关键词：P-糖蛋白；吸收；抑制剂

    中图分类号：R977.6文献标识码：A文章编号：1672-979X(2008)05-0067-03

    Contribution of Intestinal Transporters P-glycoprotein in Drug Absorption

    HU Zheng-ting

    (Center of Research on Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin 150076, China)

    Abstract：P-glycoprotein (P-gp), a kind of membrane transport proteins, can pump drugs from cells and make a low bioavailability. This overview explains the influence of P-gp on drug absorption.

    Key words：P-glycoprotein; absorption; inhibitor

    P-糖蛋白(P-glycoprotein ......