摘要：代谢组学主要考察生物体系受刺激或扰动后其内源性代谢产物的变化，从而研究生物体系的代谢途径。代谢指纹分析技术是代谢组学常用的研究手段之一。本文对代谢组学及代谢指纹分析技术的研究进展作相应的论述。

    关键词：代谢组学；分析技术；代谢指纹分析

    中图分类号：Q493.1文献标识码：A文章编号：1672-979X(2008)09-0062-04

    Progress on Metabolic Fingerprinting Analysis in Metabonomics

    SUN Xiang-ming, DU Juan, NAN Li-li

    (1. Research Center on Life Sciences and Environmental Sciences, Harbin University of Commerce; 2. Engineering Research Center on Natural Anticancer Drugs of Ministry of Education, Harbin 150076, China)

    Abstract：Metabonomics mainly investigates the change of endogenous metabolism of biological system that is stimulated or disturbed, and studies the metabolic pathways of biological system. Metabolic fingerprinting analytical technique is one commonly used study method in metabonomics. This paper reviews the progress on metabonomics and metabolic fingerprinting analytical technique.

    Key words：metabonomics; analytical technique; metabolic fingerprinting analysis

    1代谢组学简介

    1.1代谢组学的概念

    代谢组学是通过考察生物体系受刺激或扰动后(某个特定的基因变异或环境变化)其代谢产物的变化或随时间的变化 ......