依达拉奉联合低分子肝素治疗急性脑梗死60例疗效观察
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[摘要]目的：评价依达拉奉注射液联合低分子肝素(LMWH)治疗急性脑梗死(ACI)的疗效。方法：采用随机对照试验，选择发病 48 h内的急性脑梗死患者120例，随机分为治疗组和对照组，每组各60例。治疗前1个月及治疗后1个月分别同时进行中国神经功能缺失评分(CSS)、美国国立卫生研究所脑卒中评分(NIHSS)和改良Barthel指数(MBI)比较，作为主要疗效判断标准。结果：治疗后30 d，治疗组NIHSS和CSS均明显降低，MBI明显提高。表明依达拉奉联合低分子肝素组患者的神经功能缺损恢复程度优于对照组。结论：依达拉奉是一种治疗急性缺血性脑卒中有效的神经保护剂。
[关键词]依达拉奉；急性脑梗死；低分子肝素；疗效
[中图分类号]R743.33[文献标识码]B [文章编号]1673-7210(2007)11(b)-041-02
The effects observation of edaravone associate with LMWH on 60 cases of acute cerebral infarction
ZHANG Xiao-yan, ZHAO Jin-xiu,ZHANG Ke
(Department of Internal Medicine,Baishankuang Hospital,Wanbei Coal-electricity Co.Ltd,Huaibei235154, China)
[Abstract]Objective:To investigate the effects of edaravone associate with LMWH on acute cerebral infarction(ACI). Methods:A randomized controlled study was performed.120 patients,who had an onset of ACI within 48 hours,were allocated to edaravone group(n=60) and the control group(n=60) randomly. 30 days before and after the treatment,CSS, NIHSS and MBI were evaluated.Results：There were significant differences between edaravone associate with LMWH group ......
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