干扰素联合化疗治疗晚期原发肝癌31例
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[摘要] 目的:观察干扰素联合化疗治疗晚期原发肝癌的疗效。方法:58例晚期原发肝癌随机分为对照组和观察组,对照组采用ADF方案:阿霉素(ADM)40~50 mg,d1,顺铂(DDP)20 mg,d1~5,5-氟尿嘧啶(5-FU)500 mg,d1~5;观察组在此基础上加用干扰素6 000 000 U,皮下注射,隔日1次,连用4~6周。结果:观察组:PR16%(5/31),NC25%(8/31),(PR+NC)41%;一年生存率22.5%(8/31),中位生存期32周;对照组:PR11%(3/27),NC18%(5/27),(PR+NC)29%。一年生存率14.8%(4/27),中位生存期28周。两组相比,P<0.05。结论:干扰素联合化疗可以提高晚期原发肝癌的疗效。
[关键词] 干扰素;晚期原发肝癌;化疗
[中图分类号] R735.7[文献标识码]B [文章编号]1673-7210(2008)02(b)-056-02
Clinical research of interferon with chemotherapy regimen for advanced primary liver
KUANG Xian-kui1,ZHU Xiang-lin1,SI Xiao-shan1,LI Lin1,XU Li2
(1.Department of Oncology,The First People's Hospital of Xiangcheng, Xiangcheng 466200,China;2.Department of Oncology,The First Hospital of Zhengzhou University, Zhengzhou 450052,China)
[Abstract] Objective:To observe the effects of interferon with chemotherapy for patients with advanced primary liver ......
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