[摘要] 新生血管形成是很多重要眼部疾病的共同病理改变，血管内皮细胞生长因子(vascular endothelial growth factor，VEGF)是新生血管形成过程中的关键性因子。近年来，抗VEGF药物的出现给新生血管性眼病的治疗开辟了新的途径。本文就近年来抗VEGF制剂在眼部新生血管性疾病的应用和副作用方面予以综述。

    [关键词] 新生血管性眼病； VEGF；治疗；副作用

    [中图分类号] R771[文献标识码]A [文章编号]1673-7210(2008)05(c)-028-03

    Anti-VEGF therapies for ocular neovascular disease

    LUO Ling , ZHANG Mao-nian

    (Department of Ophthalmology, the General Hospital of PLA, Beijing 100853,China)

    [Abstract] Angiogenesis is the main pathologic characters in many important ocular diseases. Vascular endothelial growth factor has been identified as playing a key role in ocular angiogenesis. In recent years, anti-VEGF therapies have shown unprecedented efficacy in treating ocular neovascular disease. This review will focus on the anti-VEGF for the current treatment of ocular neovascular disease and its side effects.

    [Key words] Ocular neovascular disease；VEGF；Treatment；Side effects

    眼新生血管形成是很多眼部疾病的共同病理改变 ......