TLR4受体在肝癌细胞株HepG-2的表达(2)
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本实验从基因的角度证明了肝癌细胞株HepG-2中有TLR4基因的转录,从蛋白的角度证实了肝癌细胞株HepG-2中有TLR4蛋白的表达,表明肝癌细胞株HepG-2有TLR4的表达。HepG-2细胞株是目前国际公认的肝癌细胞株,对于肝癌发生、发展、侵袭、转移甚至肝癌的治疗的许多研究都是利用HepG-2细胞株来完成的,本实验证明了肝癌细胞株表面有TLR4的表达,为今后对TLR4在肝癌中的作用及其作用途径的研究提供了实验对象,同时也未今后利用TLR4进行肿瘤治疗提供了实验对象。
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(收稿日期:2008-02-27)
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