博乐欣与西酞普兰治疗抑郁症对照研究
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[摘要] 目的：探讨博乐欣与西酞普兰治疗抑郁症的疗效与安全性。方法：86例抑郁症患者随机分为2组，分别给予博乐欣与西酞普兰治疗，疗程6周。采用汉密尔顿抑郁量表(HAMD)评价疗效，同时观察不良反应。结果：治疗3，6周末，两组的HAMD总分均较治疗前显著减低(P<0.01)；治疗6周末，博乐欣组与西酞普兰组的有效率分别为90.2%，87.5%(P>0.05)；两组不良反应相当且轻微。结论：博乐欣与西酞普兰治疗抑郁症疗效相当，均安全有效。
[关键词] 抑郁症；博乐欣；西酞普兰；疗效；不良反应
[中图分类号] R971+.43 [文献标识码]B[文章编号]1673-7210(2008)07(c)-069-02
A control study of venlafaxine and citalopram in treatment of depression
FAN Zuo-jun
(The First Mental Hospital of Hengyang City，Hengyang 421002，China)
[Abstract] Objective:To investigate the efficacy and safety of venlafaxine and citalopram in treating the patients with depression. Methods:86 patients with depression were randomly divided into two groups which were treated with venlafaxine and citalopram for 6 weeks respectively. Hamilton Depression Scale(HAMD) was employed to evaluate efficacy，and side effects were observed.Results: The HAMD scores of both groups significantly reduced at weeks 3 ......
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