Synthesis of unsaturated fatty acid derivatives of 4-aminosalicylic ac(4)

http://www.100md.com 2010年3月25日 Jiang Aiwen,Zhao Zhengbao

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    参见附件。

     [1]Clara Abraham, Judy H. Inflammatory bowel disease [J]. The new England Journal of Medicine,2009,361(21):2066-2078.

    [2]W. Beeken, D. Howard, J. Bigelow, et al. Controlled trial of 4-ASA in ulcerative colitis [J]. Digestive Diseases and Science,1997,42(2):354.

    [3]Y. J. Jung, J. S. Lee, Y. M. Kim. Synthesis and in vitro/in vivo evaluation of 5-aminosalicyl-glycine as a colon-specific prodrug of 5-aminosalicylic acid [J]. Journal of Pharmaceutical Sciences,2000,89(5):594.

    [4]D. C. Pearson, D. J Heuil, et al. The anti-oxidant properties of 5-aminosalicylic acid [J]. Free Radical Biology & Medicine,1996,21(3):67-373.

    [5]W. G. Jin. Production of pharmaceutical intermediates and practical technical manuals [M]. Beijing: Chemical Industry Press,2002:279.

    [6]R. P. Li, W. C. Zhou, W. L. Zhou. Synthesis and antibacterial activity of (S)-5-acetamidomethyl-3-[(3-chloro-4-substituted aminomethyl)phenyl]-2-oxazolidinones [J]. Chinese Journal of Pharmaceuticals,2007,(38)3:205.

    [7]S. F. Sheng, H. X. Zheng, J. Liu, et al. Synthesis of azo derivatives of 4-aminosalicylic acid [J]. Chin Chem Lett,2008,19(4):419.

    (received date: 2009-12-11)

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