米非司酮对子宫肌瘤患者血清IL-6和TNF-α的影响(1)
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[摘要] 目的:观察子宫肌瘤患者服用米非司酮治疗后,血清白细胞介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)浓度的改变,探讨米非司酮对子宫肌瘤患者的治疗作用。方法:随机选择子宫肌瘤患者86例,每日口服米非司酮10 mg,连用3个月,观察患者治疗前后血清IL-6和TNF-α的变化。结果:子宫肌瘤患者血清IL-6和TNF-α水平总体高于正常人,经米非司酮治疗后,血清IL-6和TNF-α均降低。结论:米非司酮是一种安全、有效的治疗子宫肌瘤的药物。
[关键词] 米非司酮;子宫肌瘤;白细胞介素-6;肿瘤坏死因子-α
[中图分类号]R711.74 [文献标识码]B [文章编号]1673-7210(2010)04(b)-057-02
The influence of Mifepristone on the IL-6 and TNF-α in hysteromyoma
XIN Hua1, ZHOU Wei2, DENG Weixiong1, ZHENG Dingrong2
(1.Maternity and Child Care Hospital, Bao'an District of Shenzhen, Shenzhen 518101, China; 2.Xixiang People's Hospital, Bao'an District of Shenzhen, Shenzhen 518102, China)
[Abstract] Objective: To observe the concentration changes of serum interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in the patients with hysteromyoma who were treated by Mifepristone, and explore the treatment effect of Mifepristone in the treatment of hysteromyoma ......
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