早产低体重儿控温湿化氧疗的效果观察(1)
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[摘要] 目的:探讨控温湿化氧疗对低出生体重儿低氧血症的治疗效果及安全性。方法:120例早产低体重并低氧血症患儿随机分为两组,治疗组60例,给予恒温湿化氧疗;对照组60例,给予传统湿化氧疗,观察两组低氧血症的改善效果。结果:与对照组比较,治疗组氧疗时间、复温时间及住院时间均明显缩短(P<0.01),血氧饱和度升高值提高(P<0.01),疗效增强(P<0.05),且并发症明显减少(P<0.01)。结论:智能控温湿化氧疗较传统湿化氧疗更有效和安全。
[关键词] 早产儿;低出生体重儿;低氧血症;智能控温湿化氧疗
[中图分类号] R714.21[文献标识码]A [文章编号]1673-7210(2010)06(a)-018-02
Clinical observation of temperature controlling humidified oxygen therapy on preterm low birth weight infants
LI Meizhen1, YANG Shuguang2, ZHANG Chunli3
(1.Guangming Hospital of Guangming New District, Shenzhen City, Shenzhen 518107, China; 2.Department of Pediatrics, Gongming Hospital of Guangming New District, Shenzhen City, Shenzhen 518106, China; 3.Department of Pediatrics, Maternal and Child Health Hospital of Bao'an District, Shenzhen City, Shenzhen 518100, China)
[Abstract] Objective: To observe the clinical effect and safety of temperature controlling humidified oxygen therapy on preterm low birth weight infants. Methods: 120 infants with preterm low birth weight were randomly divided into two groups: therapy group (60 cases) was given homeothermia humidified oxygen therapy; control group was given conventional humidified oxygen therapy. The clinical effect of hypoxemia was observed in every group. Results: Compared with the control group, therapy group showed reduced oxygen therapy time, rewarming time and length of stay (P<0.01) and increased increment of saturation of blood oxygen (P<0.01), the effect was enhanced (P<0.05). The side effect of therapy group was significantly less than that of the control group (P<0.01). Conclusion: Temperature controlling humidified oxygen therapy may be more efficient than conventional humidified oxygen therapy and has less adverse effect on hypoxemia of preterm low birth weight infants.
[Key words] Preterm infant; Low birth weight infant; Hypoxemia; Intelligence temperature controlling humidified oxygen therapy
早产低出生体重(孕周少于37周且体重低于2 500 g)新生儿常伴低氧血症而需氧疗[1]。鉴于高压氧疗易致早产儿视网膜病变(ROP)和支气管肺发育不良(BPD)等氧中毒后遗症[2],目前国内多采用传统灭菌室温蒸馏水湿化常压氧疗对早产低体重儿进行救治,但该方法供氧温化、湿化不足且无氧浓度控制,可致低体温、气道收缩、耗氧量及不显性失水增加、肺表面活性物质活性降低及易诱发ROP和BPD等不良后果[3-4],影响患儿治疗效果,甚至影响生存质量[5] ......
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