奇正消痛贴治疗膝骨关节炎的疗效观察(1)
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[摘要] 目的：观察奇正消痛贴治疗膝骨关节炎的临床疗效。方法：将我院70例膝骨关节炎患者随机分为A组(奇正消痛贴组)和B组(双氯芬酸钠片组)，每组各35例。治疗1周后观察评定其治疗效果。结果：A组总有效率为86.67%，优良率为43.33%；B组总有效率为84.38%，优良率为40.63%。两组总有效率和优良率比较，差异均无统计学意义(均P>0.05)。结论：奇正消痛贴在治疗膝骨关节炎导致的疼痛、关节活动度受限的疗效较口服非甾体抗炎药(NSAIDs)的疗效略好。因此，综合考虑首选奇正消痛贴治疗膝骨关节炎应该是可行的，尤其对于原有胃十二指肠、肝肾疾病及心血管等疾病的患者。
[关键词] 膝骨关节炎；奇正消痛贴；疗效
[中图分类号] R684.3 [文献标识码] B [文章编号] 1673-7210(2011)11(c)-173-02
Observation of curative effects on Qizheng Relieving-pain Paste in the treatment of knee osteoarthritis
LU Tao, LI Wen
Department of Orthopedics, the Affiliated Drum Tower Hospital of Nanjing University, Jiangsu Province, Nanjing 210008, China
[Abstract] Objective: To observe the curative effects of Qizheng Relieving-pain Paste in the treatment of knee osteoarthritis. Methods: 70 patients were randomly divided into the group A of Qizheng Relieving-pain Paste with 35 patients and the group B of Diclofenac Sodium Tablets with 35 patients. The curative effects were observed and assessed after treatment for one week. Results: The effective rate of group A was 86.67%, and the group B was 84.38%, the good rate of group A was 43.33%, and the group B was 40.63%; with no significant difference between the effective rate and good rate of the two groups (all P>0.05). Conclusion: Qizheng Relieving-pain Paste has more curative effects compared with the oral NSAIDs in the treatment of treating pain and limitation of range of motion caused by knee osteoarthritis. So the preferred use of Qizheng Relieving-pain Paste in the treatment of knee osteoarthritis should be feasible, especially for patients with gastroduodenal disease, liver and kidney disease and cardiovascular disease.
[Key words] Knee osteoarthritis; Qizheng Relieving-pain Paste; Curative effects
骨关节炎(OA)是一种常见的以关节软骨和软骨下骨破坏为主要特点的难治性、慢性退行性病变，发病率随年龄的增长而增加。它是导致老年人行动障碍的最常见原因之一。膝关节作为主要负重关节，是骨关节炎中最易受累的关节之一。选择疗效确切而不良反应小的治疗方法对患者是重要的。奇正消痛贴膏是西藏奇正藏药公司根据藏医传统验方，结合多年临床实践，选用西藏高原特有的天然野生药材独一味、水柏枝等中药材，应用现代超低温真空脱水冻干技术工艺精心研制而成的纯正藏药。该药具有较强的强筋骨、散瘀痛、祛风湿、除痿痹的作用，对骨关节炎疼痛有良好的治疗作用。本文通过对奇正消痛贴治疗膝骨关节炎的临床疗效观察，探讨其在治疗膝骨关节炎中的作用，以利治疗。
1 资料与方法
1.1 一般资料
选取2010年5月~2010年10月我院收治的70例膝骨关节炎患者，共78个膝关节，单侧62例，双侧8例。急性发作疼痛病程3 d~6周。将所有患者随机分为A组(奇正消痛贴组)和B组(双氯芬酸钠肠溶片组)，每组各35例。A组失访5例，随访30例；男9例 ......
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