重型颅脑外伤性脑梗死相关危险因素的回归分析(1)
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[摘要] 目的：探讨重型颅脑外伤性脑梗死相关危险因素。方法：对245例重型颅脑损伤患者的性别、年龄、是否手术、手术方式、是否合并糖尿病和高血压、脑疝、是否低血压休克、住院时间等18个外伤后脑梗死(PTCI)相关危险因素，进行单因素和非条件Logistic回归分析。结果：PTCI 51例，经单因素和Logistic回归分析可知，年龄、休克或低血压、脑疝及糖尿病为PTCI发生的危险因素(P<0.05)，活血药物使用为保护因素。结论：年龄、休克或低血压、脑疝及糖尿病为PTCI发生的危险因素，对该病的防治有一定临床意义。
[关键词] 颅脑外伤；外伤性脑梗死；危险因素
[中图分类号] R651.1+5 [文献标识码] A [文章编号] 1673-7210(2012)01(a)-037-02
Regression analysis of risk factors of severe head trauma with posttraumatic cerebral infarction
QIAO Zhizheng1, WANG Feng2
1.Department of Neurosurgery, the People's Hospital of Pingyi County, Shandong Province, Pingyi 273300, China; 2.Department of Neurosurgery, the People's Hospital of Yishui County, Shandong Province, Yishui 276400, China
[Abstract] Objective: To investigate risk factors of severe head trauma with posttraumatic cerebral infarction. Methods: 18 risk factors of PTCI of 245 patients with severe head trauma were retrospectively reviewed, including gender, age, whether operation, operating style, whether complicate with hypertension, diabetes and brain herniation, low blood pressure or shock, hospital stay time and so on. The factors were analyzed by univariate and regression analysis. Results: There were 51 cases suffered in PTCI. There were significant relationship between age, low blood pressure or shock, brain herniation, diabetes and PTCI (P<0.05), while the use of blood circulation promoting drugs was a protective factor of PTCI. Conclusion: Age, low blood pressure or shock, brain herniation, diabetes are risk factors to severe head trauma with posttraumatic cerebral infarction, they may have a certain clinical significance to prevent and control of this disease.
[Key words] Severe head trauma; Post-traumatic cerebral infarction; Risk factor
外伤后脑梗死(post-traumatic cerebral infarction，PTCI)是颅脑损伤后严重并发症之一，尤其是大面积脑梗死，一旦发生，则加重脑功能损害，导致病情急剧恶化，严重影响患者预后。重型颅脑外伤由于病情危急，如临床处理不当更易继发脑梗死。国内有关PTCI的危险因素分析少有报道[1-2]，因此，分析颅脑损伤后发生PTCI的危险因素，有利于降低PTCI的发生率，对尽早改善患者临床治疗和患者预后具有重要临床意义。
1 资料与方法
1.1 一般资料
选取2009年5月~2010年8月我院脑外科收治的245例重型颅脑外伤患者，其中，男164例，女81例；年龄均大于18周岁 ......
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